Tiroid hastalıkları, gebelik esnasında kompleks hormonal değişiklikler nedeniyle yaygın olarak görülür. Fetal hidrops, düşük doğum ağırlığı, fetal distress ve nörofizyolojik gelişme geriliği açısından risklidir. 20 yaşında primigravid gebe hipotiroidizmle başvurdu ve bu esnada propiltiourasil (PTU) 3x1 kullanmaktaydı. Yapılan ultrasonografi (USG)’de hidrops fetalis görüldü ve bunun üzerine PTU ...

Cardiotocography is one of the most widely used technique for recording changes in fetal heart rate (FHR) and uterine contractions. Assessing cardiotocography is crucial in that it leads to identifying fetuses which suffer from lack of oxygen, i.e. hypoxia. This situation is defined as fetal distress and requires fetal intervention in order to prevent fetus death or other neurological disease c...

We performed a prospective clinical evaluation of our newly developed fluorescence polarization procedure to predict fetal lung maturity (Clin Chem 1986;32:248-54). Net fluorescence polarization was measured at 34 degrees C after a 6.5-min incubation of amniotic fluid with fluorophore. For the 26 cases of neonatal respiratory distress syndrome encountered in 196 deliveries, the net polarization...

Background: This hospital-based, prospective, comparative interventional study aimed to compare the effectiveness of sublingual misoprostol and intracervical dinoprostone gel for induction labor in primigravida women. Methods: A total 100 patients were alternately assigned with either Misoprostol 25mcg 6 hourly or Gel 0.5mg hourly. Results: The delivery interval was significantly longer group c...

Ageing is an unavoidable corollary to being alive; the most intuitive interpretation of ageing being that it is the consequence of progressive body degeneration. In agreement with this, current models propose that ageing occurs through a stepwise accumulation of DNA damage, which ultimately limits the regenerative capacity of tissues. On the other hand, there is increasing evidence that fetal d...

OBJECTIVE The aim of this study was to investigate perinatal outcome and the rate of cesarean section (CS) following intrapartum amnioinfusion in women with meconium-stained amniotic fluid (MSAF). METHOD A total of 100 women at term in labor with meconium were randomized to infuse transcervical intrapartum amnioinfusion with saline (50) and routine obstetrical care (50). Perinatal outcome and...

To assess teratogenic effects of cocaine exposure and maternal psychological distress on birth outcomes, we conducted a longitudinal prospective study of 415 infants (218 cocaine-exposed--CE, 197 nonexposed--NE). Drug exposure was determined through a combination of maternal self-report, urine, and meconium screens. Maternal psychological distress postpartum was evaluated through a standardized...

762 women were screened for GBS-carriership in the first trimester of pregnancy. The mean age of carriers was 27.2 years. Follow-up was performed in 64 initially positive and 97 negative cases. Persistent carriership was the most important determinant for neonatal GBS-acquisition. Race, birth-weight, gestational-age, interval between rupture of the membranes and birth could not be associated wi...