Coenzyme Q10 (CoQ10), an important antioxidant molecule playing a major role in electron transport chain, has been commercially produced by fermentation process for the use in oral nutraceutical formulations. Constructing the high-yielding CoQ10 producing strains is a pre-requisite for cost-effective production. A superior mutant strain P-87 generated from Paracoccus denitrificans ATCC 19367, w...

Designing large-scale stirred bioreactors with performance closely matching the one achieved in lab-scale fermenters presents continuous challenge. In this contribution, dynamic modelling of the aerobic biocatalytic conversion process in viscous batch stirred tank reactor is developed. Its operation is illustrated by simulation of the interaction of fluid flow, mass transfer and reaction releva...

Abstract A biogas plant is fed with agricultural substrates at an average organic loading rate of 6 kg VS per m 3 fermenter volume day and relatively high nitrogen content. This situation results in a below‐average methane yield, so the aim to increase substrate efficiency. An analysis actual condition was performed compared reference values. dynamic simulation model created adjusted data over ...

This study presents a methodological framework for auditing, optimization as well the integration of hybridized solar energy in Ghana’s agro-industrial sector. The Functional Analysis System Technique was introduced systematically translating plant-wide requirements into detailed functional and performance design criteria efficiency, optimization, integration. results case indicated that insula...