نتایج جستجو برای: fed rat

تعداد نتایج: 355137  

Journal: :The Journal of nutrition 2010
Timothy D Swartz David M Savastano Mihai Covasa

Adult rats chronically fed a high-fat (HF) diet maintain reduced sensitivity to cholecystokinin (CCK). We hypothesized that, similar to adult rats, pups fed a HF diet would also exhibit reduced sensitivity to CCK. To test this, male pups fed low-fat (LF) and HF isoenergetic (16.2 kJ/g) diets were administered CCK intraperitoneally (0.125-1 microg/kg) 1 wk following dietary adaptation. After rec...

Journal: :Phytomedicine : international journal of phytotherapy and phytopharmacology 2008
Shirin Hooshmand Anju Balakrishnan Richard M Clark Kevin Q Owen Sung I Koo Bahram H Arjmandi

Postmenopausal bone loss is a major public health concern. Although drug therapies are available, women are interested in alternative/adjunct therapies to slow down the bone loss associated with ovarian hormone deficiency. The purpose of this study was to determine whether dietary supplementation of l-carnitine can influence bone density and slow the rate of bone turnover in an aging ovariectom...

Journal: :World Journal Of Advanced Research and Reviews 2022

The Carcite type of Corbicula japonica shell powder developed at high temperature 500℃ had improved mal-function liver in the LEC rat disorder model, and restored its function. Additional a new bio-function fired was lately found to lower blood sugar level Type 2 diabetes model mouse (KK/TaJcl). These mice were raised with 2.5% for month showed significant 81±23mg that control without 208±86mg ...

2006
Hishashi Shinozuka Benito Lombardi Stewart Sell Richard M. lammarino

The effects of feeding a choline-deficient (CD) or a choline-supplemented diet upon the early stages of DLethionine carcinogenesis in rat liver were investigated. Low levels of ou-ethionine (0.05 and 0.10%) when fed with a CD diet were found to induce within 4 weeks a massive proliferation of oval cells without significant cell necrosis or presence of inflammatory cell infiltrates. The same lev...

Journal: :American journal of physiology. Endocrinology and metabolism 2007
Lucie Sedová Ondrej Seda Ludmila Kazdová Blanka Chylíková Pavel Hamet Johanne Tremblay Vladimír Kren Drahomíra Krenová

The importance of early environment, including maternal diet during pregnancy, is suspected to play a major role in pathogenesis of metabolic syndrome and related conditions. One of the proposed mechanisms is a mismatch between the prenatal and postnatal environments, leading to misprogramming of the metabolic and signaling pathways of the developing fetus. We assessed whether the exposure to h...

2013
Min-Chuan LAI Tzu-Hua TENG Chi YANG

Free fatty acids play an important role in regulating animal insulin secretion response. Acute elevated free fatty acids increased animal insulin secretion and glucose-stimulated insulin secretion. In the present study, we perfused the rat pancreas to explore the effect of unsaturated fatty acids on insulin secretion. The results showed that linoleic acid, γ-linolenic acid and arachidonic acid ...

Journal: :The Journal of clinical investigation 1978
D H Van Thiel J S Gavaler R Lester

The effect of ethanol feeding on ovarian function and structure in female rats was studied in alcohol-fed animals, isocalorically fed controls, and two ad libitum-fed control groups. Ovarian weight was reduced by 60% in alcohol-fed animals compared with the control groups. Gross disruption of ovarian architecture was noted, characterized by the absence of any corpus hemorrhagicum and corpus alb...

2011
Rinat R. Ran-Ressler Ludmila Khailova Kelly M. Arganbright Camille K. Adkins-Rieck Zeina E. Jouni Omry Koren Ruth E. Ley J. Thomas Brenna Bohuslav Dvorak

INTRODUCTION Branched chain fatty acids (BCFA) are found in the normal term human newborn's gut, deposited as major components of vernix caseosa ingested during late fetal life. We tested the hypothesis that premature infants' lack of exposure to gastrointestinal (GI) BCFA is associated with their microbiota and risk for necrotizing enterocolitis (NEC) using a neonatal rat model. METHODS Pups...

2012
Sunil Joshi Benjamin T. Saylor Wei Wang Ammon B. Peck Saeed R. Khan

PURPOSE We have previously shown that production of reactive oxygen species (ROS) is an important contributor to renal injury and inflammation following exposure to oxalate (Ox) or calcium-oxalate (CaOx) crystals. The present study was conducted, utilizing global transcriptome analyses, to determine the effect of Apocynin on changes in the NADPH oxidase system activated in kidneys of rats fed a...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2012
Jan M Williams Fan Fan Sydney Murphy Carlos Schreck Jozef Lazar Howard J Jacob Richard J Roman

This study examined whether substitution of chromosome 5 containing the CYP4A genes from Brown Norway rat onto the Dahl S salt-sensitive (SS) genetic background upregulates the renal production of 20-HETE and attenuates the development of hypertension. The expression of CYP4A protein and the production of 20-HETE were significantly higher in the renal cortex and outer medulla of SS.5(BN) (chrom...

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