Objective: Different follicular dendritic cells (FDCs) meshwork patterns were observed in small B-cell lymphomas (SBL) specimens. However, the accurate CD21 and CD23 expression differences in both follicular dendritic cells (FDCs) and tumor cells in SBLs were not sufficiently investigated. Methods: CD21 and CD23 immunostainings were performed on our surgically resected SBL samples to compare th...

BACKGROUND The purpose of this study was to explore the budget impact of dutasteride plus tamsulosin fixed-dose combination (DUT + TAM FDC) versus tamsulosin monotherapy, in the treatment of patients with benign prostatic hyperplasia (BPH) from the perspective of the Greek healthcare insurance system. METHODS A Microsoft Excel-based model was developed to estimate the financial consequences o...

The validity of the assumption that the specific growth rate of coccoid microorganisms can be expressed as the absolute value of the derivative of frequency of dividing cells (FDC) with respect to time was tested experimentally using a Microcystis aeruginosa strain. FDC was calculated based on the assumption that elongated cells, constricted cells or both may correspond to dividing cells. The s...

Follicular dendritic cells (FDCs) retain and display opsonized antigens in primary follicles and germinal centers (GCs). However, their roles beyond antigen presentation have been incompletely defined. In this study, we tested the impact of selective FDC ablation on short-term follicle and GC function. Within 2 d of FDC ablation, primary follicles lost their homogeneity and became disorganized ...

Since the ras family of proto-oncogenes is supposed to be involved in leukemogenesis by point-mutational activation, we studied the effect of the activated ras gene on the growth of a murine interleukin-3 (IL-3)dependent cell line, FDC-P2. The human activated c-H-ras gene was transfected into FDC-P2 cells by electroporation using a high-level expression vector, BMGhph, which contains a partial ...

Purpose A new fixed-dose combination (FDC) formulation of telmisartan 80 mg and S-amlodipine 5 mg (CKD-828) has been developed to increase convenience (as only one tablet is required per day) and improve treatment compliance. Methods The pharmacokinetic characteristics and tolerability of an FDC of telmisartan and S-amlodipine were compared to those after coadministration of the individual ag...

This study investigated the useful morphologic and immunophenotypic findings for the diagnosis of Castleman's disease (CD). We focused on the distribution and expression of follicular dendritic cells (FDC) in lymphoid follicles from patients with CD. Eleven CD cases of the hyaline vascular (HV) variant and six cases of the plasma cell (PC) variant were studied using tissue microarray and paraff...

PURPOSE The fixed-dose dual bronchodilator combination (FDC) of tiotropium and olodaterol showed increased effectiveness regarding lung function and health-related quality of life in patients with chronic obstructive pulmonary disease (COPD) compared with the use of its mono-components. Yet, while effectiveness and safety have been shown, the health economic implication of this treatment is sti...

OBJECTIVE Failure to decrease blood pressure (BP) during the night is associated with higher cardiovascular (CV) morbidity and mortality. There is strong evidence that fixed-dose combinations (FDCs) of antihypertensive agents are associated with significant improvement and non-significant adverse effects. The aim of the present study was to evaluate whether FDC affected nocturnal BP favorably i...

This paper presents a quantization noise cancellation technique for frequency-to-digital converter-based fractional-N phase-locked loops (FDC-PLLs). The technique cancels quantization noise prior to the loop filter so the PLL bandwidth can be increased without a significant phase noise penalty. The paper also presents an FDC-PLL architecture enhancement that achieves the effect of a charge pump...