Background. Anemia during pregnancy is commonly caused by iron deficiency and can have severe consequences for both the mother and the developing fetus. The aim of this retrospective study was to assess the safety and efficacy of intravenous ferric carboxymaltose (FCM) in pregnant women. Methods. All women treated with FCM for anemia during pregnancy between 2010 and 2012 at our institution wer...

CD19 and CD20 are B cell-specific antigens whose expression is heterogeneous when analyzed by flow cytometry (FCM). We determined the association between CD20 expression and clinical outcome in patients with diffuse large B-cell lymphoma (DLBCL). The mean fluorescence intensity of CD20 and CD19 was determined by FCM, and the cytoplasmic expression of CD20 was determined by immunohistochemistry ...

−Segmentation is a difficult and challenging problem in the magnetic resonance images, and it considered as important in computer vision and artificial intelligence. Many researchers have applied various techniques however fuzzy c-means (FCM) based algorithms is more effective compared to other methods. In this paper, we present a novel FCM algorithm for weighted bias (also called intensity in-...

Flow cytometry (FCM) was adapted to measure ploidy values in megakaryocytes isolated from normal guinea pigs and African green monkeys. The FCM approach was validated by microscopic identification of electronically sorted SN and higher ploidy cells and by comparisons with Feulgen microdensitometry on the same samples. Sorted 8N populations contained only megakaryocytes and were completely free ...

Data mining technology has emerged as a means for identifying patterns and trends from large quantities of data. Clustering is a primary data description method in data mining which group’s most similar data. The data clustering is an important problem in a wide variety of fields. Including data mining, pattern recognition, and bioinformatics. It aims to organize a collection of data items into...

BACKGROUND Treatment with parenteral iron causes oxidative stress, inflammation and endothelial dysfunction. Ferric carboxymaltose (FCM) is a new preparation of non-dextran iron which, due to its pharmacokinetics and stability, may induce less toxicity than other iron molecules. The aim of this study was to analyse the effect of FCM on inflammation and adhesion molecules in chronic kidney disea...

This article presents a study of academic performance evaluation using soft computing techniques inspired by the successful application of K-means, fuzzy C-means (FCM), subtractive clustering (SC), hybrid subtractive clustering-fuzzy C-means (SC-FCM) and hybrid subtractive clustering-adaptive neuro fuzzy inference system (SC-ANFIS) methods for solving academic performance evaluation problems. M...

Data deals with the specific problem of partitioning a group of objects into a fixed number of subsets, so that the similarity of the objects in each subset is increased and the similarity across subsets is reduced. Several algorithms have been proposed in the literature for clustering, where k-means clustering and Fuzzy C-Means (FCM) clustering are the two popular algorithms for partitioning t...

Flow cytometry (FCM) was adapted to measure ploidy values in megakaryocytes isolated from normal guinea pigs and African green monkeys. The FCM approach was validated by microscopic identification of electronically sorted SN and higher ploidy cells and by comparisons with Feulgen microdensitometry on the same samples. Sorted 8N populations contained only megakaryocytes and were completely free ...

Chronic lymphocytic leukemia (CLL) is a B-cell malignancy in need of new, effective, and safe therapies. The recently identified IgM receptor FcmR is overexpressed on malignant B cells in CLL and mediates the rapid internalization and lysosomal shuttling of IgM via its Fc fragment (Fcm). To exploit this internalization and trafficking pathway for targeted drug delivery, we engineered an IgM-der...