OBJECTIVE The objective of the study was to assess the effectiveness of adalimumab as a treatment for fatigue in patients with rheumatoid arthritis (RA). METHODS Fatigue was monitored in patients with RA who were already on an adalimumab treatment regimen. Fatigue, general well-being, comorbidities, and disease activity were measured at baseline and ~8, 16, and 24 weeks, thereafter. RESULTS...

In this paper we focus on the modeling and evaluation of performance factors as human fatigue at joint level. We introduce the concept of half-joint pair to calculate fatigue at joint level, that is, at muscle groups level. The fatigue model is designed to enable to a posture optimization algorithm to adapt the human posture so that when fatigue appears it can be reduced. An Inverse Kinematics ...

BACKGROUND Fatigue is a crucial sensation that triggers rest, yet its underlying neuronal mechanisms remain unclear. Intense long-term fatigue is a symptom of chronic fatigue syndrome, which is used as a model to study the mechanisms underlying fatigue. METHODS Using magnetic resonance imaging, we conducted voxel-based morphometry of 16 patients and 49 age-matched healthy control subjects. ...

OBJECTIVES This study of Japanese dual-earner couples examined the impact of family and job demands on one's own and one's partner's fatigue as well as gender differences in these effects. METHODS A total of 2,502 parents (1,251 couples) were surveyed using a self-administered questionnaire. A crossover model was tested using structural equation modeling. RESULTS The results of structural e...

Fatigue failures caused by cyclic stresses are commonly modeled by Birnbaum-Saunders (B-S) and Weibull distributions. Sometimes, materials with high cycle fatigue exhibit bimodal failure rates which are difficult to model with Weibull distribution. The objective of this paper is to investigate a general Birnbaum-Saunders (GB-S) distribution which covers diverse hazard rates such as increasing, ...

In this work a torque assessment approach is presented to estimate FES-induced torque no matter the muscle is fatigued or not in interrupted stimulation. This approach is based on evoked EMG (eEMG) signal and use peakto-peak (PTP) amplitude and second phase area (SPA) to correlate eEMG and torque. The mapping function is built with pooled data of recruitment test and fatigue test in two complet...

Fatigue damage is an irreversible progression which can be represented by the entropy increase, and it is well known that the second law of thermodynamics can describe an irreversible process. Based on the concept of entropy, the second law of thermodynamics can provide the changing direction of system. In the current study, a new entropy increment model is developed based on the frame work of ...

The available learning and forgetting models do not consider the physical loading that performing a task requires. In some situations, physical loading results in workers’ fatigue on the job that is followed by rest breaks to alleviate it. The aim of this paper is to present the "learningforgetting-fatigue-recovery model" (LFFRM) that addresses possible issues relating to workers’ capabilities ...

Residual compressive stress can improve fretting fatigue strength. In this paper, the effects of residual stress on fretting fatigue of Al 2024-T351 alloy specimens are studied using a numerical approach. The extended finite element method combined with the cyclic cohesive zone model is adopted to model fretting fatigue crack growth behavior. It is shown that residual stress changes the frettin...

the purpose of this study was to determine and compare blood lactate, heart rate and blood pressure responses in arm and leg exercises and to determine the relationship between these variables and fatigue time during these two modes of exercises. 8 young professional karate players (mean age 18.90±2.20) volunteered to participate in this study. the subjects completed two ergometers: arm and leg...