The authors analyzed data from almost 150,000 subjects aged 55-74 years enrolled in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial who completed a self-administered baseline questionnaire (1993-2001) that included items about family history of cancer. Male respondents reported significantly less family history of cancer than females. The relative underreporting by male respo...

the mean age of ftd onset is much younger than that of alzheimers disease. behavioral disturbances occur in early stages of ftd, and social dysfunction and personality deterioration may ensue. for this reason, it may be misdiagnosed with other psychiatric disorders. therefore, more careful observation and concern is required for proper diagnosis. our report is about a patient who was misdiagnos...

UNLABELLED Family history data are critical in the study of hereditary cancer syndromes and the identification of cancer modifier genes. PURPOSE The purpose of this study was to analyze the process for collecting and verifying reported cancer family histories and identify reporting inaccuracies among a series of women with endometrial cancer. EXPERIMENTAL DESIGN Detailed family histories we...

diabetes type 2 is a world wide spread disease with a multifactorial pathogenetic evolution. various factors like obesity, physical inactivity and poor lifestyle habits contribute to its development. the aim of this study was to verify if in young healthy sedentary male and female there is positive correlation between family history to type 2 diabetes and an increase in body weight and fat mass...

BACKGROUND We have previously demonstrated that breast cancers associated with inherited BRCA1 and BRCA2 gene mutations differ from each other in their histopathologic appearances and that each of these types differs from breast cancers in patients unselected for family history (i.e., sporadic cancers). We have now conducted a more detailed examination of cytologic and architectural features of...

PURPOSE: Histologic findings in 51 pancreata resected from patients with a strong family history of pancreatic cancer were compared with the findings in 40 pancreata resected from patients with sporadic pancreatic cancer. None of the patients in the familial group had a known inherited syndrome other than familial pancreatic cancer. EXPERIMENTAL DESIGN: Precursor lesions, including pancreatic i...

INTRODUCTION Gastric cancer is one of the major causes of cancer related death in the world. A number of risk factors are now known to be related to the development of the disease. Previous reports indicated that a family history is a serious risk, but there is a little information about this in Iran. The aim of this study was to explore the relation between family history of cancer in first an...