Age at onset is the most important feature of schizophrenia that could indicate its origin. Minor physical anomalies (MPAs) characterize potential marker indices of disturbances in early neurodevelopment. However, the association between MPAs and age at onset of schizophrenia is still unclear. We aimed to compare risk assessment and familial aggregation in patients with early-onset schizophreni...

BACKGROUND Approximately 20% of multiple sclerosis patients have a family history of multiple sclerosis. Studies of multiple sclerosis aggregation in families are inconclusive. OBJECTIVE To investigate the genetic burden based on currently discovered genetic variants for multiple sclerosis risk in patients from Dutch multiple sclerosis multiplex families versus sporadic multiple sclerosis cas...

----------------------------INDICATIONS AND USAGE ---------------------------­ ZOCOR is an HMG-CoA reductase inhibitor (statin) indicated as an adjunctive therapy to diet to: • Reduce the risk of total mortality by reducing CHD deaths and reduce the risk of non-fatal myocardial infarction, stroke, and the need for revascularization procedures in patients at high risk of coronary events. (1.1) •...

BACKGROUND Stroke is a major cause of morbidity and death in the United States. We tested the association between familial risk for stroke and prevalence of the disease among US adults and assessed the use of family history of stroke as a risk assessment tool for the disease. METHODS Using data from the 2005 HealthStyles survey (n = 4,819), we explored the association between familial stroke ...

background loneliness is one of the psychological variables related to high risk behaviors that should be investigated more. objectives the current study aimed to assess emotional, social, romantic, and familial dimensions of loneliness in drug abuser and nondrug abuser individuals. patients and methods two hundred and twenty eight individuals were enrolled in this cross sectional study. hundre...

Evidence of the accuracy of self-reported mammography use among women with familial breast cancer risk is limited. This study examined the accuracy of self-reported screening mammography dates in a cohort of 1,114 female relatives of breast cancer cases, aged 26 to 73 from the Ontario site of the Breast Cancer Family Registry. Self-reported dates were compared to dates abstracted from imaging r...

PURPOSE/OBJECTIVES To investigate how familial communication about prostate cancer (PCa) risk and screening affects sons of men with PCa. RESEARCH APPROACH Qualitative grounded theory. SETTING Southern California. PARTICIPANTS 17 Latino sons of PCa survivors. METHODOLOGIC APPROACH The team conducted semistructured interviews and follow-up interviews. Therefore, the sample includes 25 tr...

AIMS To analyse the contribution of certain social, familial, prenatal, perinatal, and developmental background factors in the pathogenesis of deficits in attention, motor control, and perception (DAMP). METHODS A population based case-control study was carried out with 113 children aged 6 years, 62 diagnosed with DAMP and 51 controls without DAMP. The children's health and medical records we...

BACKGROUND Breast cancer is the most common cancer affecting women all over the world. In addition to hormonal and environmental causes, family history is emerging as an important risk factor in the etiology of this disease. The aim of the present study is thus to compare the clinico-pathological features of familial and sporadic breast cancer in Moroccan patients. METHODS A comparative retro...

OBJECTIVES Familial clustering of chronic obstructive pulmonary disease (COPD) is well established, but the familial risk of COPD has not been determined among adoptees. The aim was to determine whether the familial transmission of COPD is related to disease in biological and/or adoptive parents. DESIGN Historic cohort study. PARTICIPANTS 80,214 (50% females). METHODS The Swedish Multi-Ge...