we present a 55-year old male patient who was subjected to whole body skeletal scintigraphy for metastatic work up of urinary bladder cancer. whole body 99mtc-methylene diphosphonate (mdp) skeletal scintigraphy was performed. that revealed no skeletal metastasis in the entire body skeleton and normally visualized left kidney with empty right renal fossa. additionally tracer activity collected i...

Molecular imaging is commonly used to improve the diagnosis and treatment of cancer. Nuclear medicine offers cutting-edge procedures instruments, computers radiopharmaceuticals for various diseases, including oncology indications. The detailed images provided by positron emission tomography (PET) can accurately image biochemical or physiologic/pathologic phenomena.

BACKGROUND Lymph node status is the key to determining the prognosis and treatment of cervical cancer. However, it cannot be assessed clinically, and testing for nodal metastasis is controversial. We sought to systematically review the diagnostic accuracy literature on sentinel node biopsy, positron emission tomography, magnetic resonance imaging and computed tomography to evaluate the accuracy...

We demonstrate the use of gold nanorods as bright contrast agents for two-photon luminescence (TPL) imaging of cancer cells in a three-dimensional tissue phantom down to 75 mum deep. The TPL intensity from gold-nanorod-labeled cancer cells is 3 orders of magnitude brighter than the two-photon autofluorescence (TPAF) emission intensity from unlabeled cancer cells at 760 nm excitation light. Thei...

Angiosarcoma is a rare entity in breast cancer patients. 18-F-Flourodeoxyglucose (FDG) Positron Emission Tomography/ Computed Tomography (PET/CT) is usually used in breast cancer patients for staging, re-staging and treatment response. Lymphangiosarcoma also called as Stewart-Treves Syndrome can be develop in the following years as a complication after therapy of breast cancer. Imaging and stag...

Cyclooxygenase-2 (COX-2) fluorescent probes are promising tools for early diagnosis of cancer. Traditionally, COX-2 were designed by connecting two parts, a fluorophore and binding unit, via flexible linker. Herein, new class COX-2-specific have been developed one-step modification from rofecoxib an integrative approach to combine the unit into one. Among them, several analogues not only exhibi...

introduction: after presbycusis, noise-induced hearing loss is the second most common cause of acquired hearing loss. numerous studies have shown that high-intensity noise exposure increases free radical species; therefore, use of antioxidants to detoxify the free radicals can prevent cellular damage in the cochlea. we studied the potential hearing protective effect of different doses of ascorb...

as a nuclear approach, positron emission tomography (pet) is a functional imaging technique which is based on the detection of gamma ray pairs emitted by a positron-emitting radionuclide. there are certain limitations to this technique such as normal tissue uptake. therefore, it has been recommended that patients prepare before scanning. fasting for a short while before pet imaging is an exampl...

the effects of unleaded gasoline and unleaded gasoline–ethanol blends on engine performance and pollutant emissions were investigated experimentally in a single cylinder, four-stroke spark-ignition engine with variable engine speeds (2600–3500 rpm). four different blends on a volume basis were applied. these are e0 (0% ethanol + 100% unleaded gasoline), e3 (3% ethanol + 97% unleaded gasoline), ...