The blood-retinal barrier (BRB) functions to maintain the immune privilege of the eye, which is necessary for normal vision. The outer BRB is formed by tightly-associated retinal pigment epithelial (RPE) cells which limit transport within the retinal environment, maintaining retinal function and viability. Retinal microvascular complications and RPE dysfunction resulting from diabetes and diabe...

22 23 24 Combined systemic and topical administration of voriconazole have been successfully used to 25 treat keratomycosis infection. No voriconazole eye drop product being commercially 26 available, we prepared a sterile eye drop solution (10 mg/ml). Voriconazole remains stable 27 over 30 days providing an eye drop solution suitable for topical treatment of fungal keratitis. 28 29 30 31 32 33...

conclusions although toxoplasmosis nr is rare, it should be considered in the differential diagnoses of nr. case presentation a 13-year-old girl presented with painless subacute visual loss in her right eye for a week at khatam-al-anbia eye hospital in mashhad, iran. following comprehensive evaluation, a diagnosis of toxoplasmic nr was made. the nr favorably responded to classic anti-toxoplasmo...

PURPOSE To compare the efficacy of each of seven expressed herpes simplex virus 1 (HSV-1) glycoproteins as vaccines to protect against ocular disease after primary ocular HSV-1 infection. METHODS Mice were vaccinated three times with equal amounts of each of seven individually expressed HSV-1 glycoproteins (gB, gC, gD, gE, gG, gH, and gI) and then ocularly challenged with McKrae, a corneal di...

A 58-year-old male patient was admitted with the complaint of burning, watering, stinging, redness and pain in both eyes after he had coronavirus disease-2019 (COVID-19) infection 3 weeks ago. It determined from anamnesis that severe vision loss right eye for about 35 years been treated some previous treatments. He a best spectacle-corrected visual acuity 'hand motion' LogMAR 0.2 left eye. The ...

ophthalmia neonatorum is generally defined as conjunctivitis occurring within one month of life. the sources of this infection are environmental organisms or the organisms colonized in the birth canal. untreated infection can cause blindness, especially if the corresponding organisms areneisseria gonorrhoeae, or chlamydia trachomatis. povidone-iodine ophthalmic solution is an effective antibact...

22 23 24 Combined systemic and topical administration of voriconazole have been successfully used to 25 treat keratomycosis infection. No voriconazole eye drop product being commercially 26 available, we prepared a sterile eye drop solution (10 mg/ml). Voriconazole remains stable 27 over 30 days providing an eye drop solution suitable for topical treatment of fungal keratitis. 28 29 30 31 32 33...

BACKGROUND To investigate the clinical relevance of two different preservative formulations, we compared 1-year incidence rates of additional coding of dry eye, ocular infection, or ocular surface disease (either dry eye or ocular infection) in open-angle glaucoma and ocular hypertension patients newly treated with latanoprost with benzalkonium chloride (BAK) or with travoprost-Z with SofZia®. ...