We have shown that the effects of wound exudates on fibroblast cultures reflect their clinical healing phenotype and can thus serve as a functional biomarker. used this assay for screening to identify compounds or compound classes with so far unknown potential chronic therapy. The selective glucocorticoid receptor agonist (SEGRA) Mapracorat was found reverse inhibitory effect several exudates. ...

Medical students often encounter patients with pleural effusion during internships and their residency. These patients do not always suffer from dyspnea and an accurate clinical examination is crucial for the diagnosis. In oral and written exams, explaining the difference between transudate and exudate is a frequent task. In this article, you can find all the important information regarding ple...

Medical students often encounter patients with pleural effusion during internships and their residency. These patients do not always suffer from dyspnea and an accurate clinical examination is crucial for the diagnosis. In oral and written exams, explaining the difference between transudate and exudate is a frequent task. In this article, you can find all the important information regarding ple...

Acute inflammation was induced in rats by subcutaneous implantation of plastic sponges, and the penetration of salicylate and naproxen into the inflammatory exudate was studied after oral dosing with these compounds. The penetration of intravenously administered 22Na and 125I-albumin was also studied. It was found that salicylate and 22Na penetrated very rapidly, reaching maximum concentration ...

The abilities of normal mouse peritoneal exudate cells and fluids to mediate in vitro cell adherence reactions to Ascaris suum juveniles were investigated. Exudates were induced by intraperitoneal injection of Sephadex G-25 or by infection with A. suum and changes in the peritoneal cell populations were determined. The presence of a heat-labile component, probably complement, and a heat-stable ...

Hamsters immunized with either noninfectious hamster type-C virus (D9) or irradiated D9 tumor cells were tested for cell-mediated immune reactivity by the macrophage migration inhibition assay. The migration of peritoneal exudate cells from immunized hamsters was significantly inhibited by either D9 virus or D9 tumor extract, but not by extract of an unrelated CELO virus-induced tumor. The viru...