The rarity of venereal granuloma in married couples is usually brought forward as a point in favour of the non-venereal origin of the disease. It appears that no authentic instance of conjugal granuloma has so far been reported in the literature. We have seen several cases of conjugal disease during the past five years and, in view of the recent articles on the subject in the Gazette, and the c...

There is strong evidence to link biological, behavioural, psychological, and social variables to health, illness and disease. But this knowledge has not been successfully incorporated into standard medical practice. There is a general accord that a simple disease-based model of clinical practice is inadequate and that there is need to change the approach of doctors to include a better understan...

Although pediatricians are well aware that influenza can be a problem for infants younger than 6 months, they may be less familiar with the high rates of influenza disease and complications among pregnant women. We provide here a summary of recent data on increased risk of influenza in pregnancy and in very young infants and on vaccine protection of these 2 groups at high-risk. Pediatricians sh...

Astroviruses were first identified over 30 years ago and the virus was soon established as an important cause of gastroenteritis, particularly in young children. Human astrovirus disease was thought to result from infection by a limited number of serotypes. However, recent studies have indicated that the extent of genetic diversity is greater than previously assumed. In addition, the widespread...

In clinical practice, broad global assessments of psoriasis disease activity and its effect on patients' quality of life are used to assess the severity of patients' disease and their response to treatment. In clinical trials, more objective, validated instruments are required. Several such instruments have been developed and continue to be developed to provide an assessment of the severity of ...

BACKGROUND Symptoms other than pain are a heavy burden for patients with either malignant or progressive nonmalignant disease and significantly reduce quality of life. OBJECTIVE This article discusses the management of symptoms of malignant or progressive nonmalignant disease in the general practice setting. DISCUSSION The approach to management of the symptoms of malignant or progressive n...

Google Internet query share (IQS) data for gastroenteritis-related search terms correlated strongly with contemporaneous national (R(2) = 0.70) and regional (R(2) = 0.74) norovirus surveillance data in the United States. IQS data may facilitate rapid identification of norovirus season onset, elevated peak activity, and potential emergence of novel strains.