Herein, we report a case of nontraumatic bilateral rhegmatogenous retinal detachment (RRD) during external beam radiotherapy for nonocular tumor, presented as an observational case study in conjunction with a review of the relevant literature. A 65-year-old male was referred to our hospital due to bilateral RRD. He underwent a biopsy for a tumor of the left frontal lobe 4 months prior to presen...

The risk of radiotherapy-related secondary cancers in children with constitutional retinoblastoma 1 (RB1) mutations has led to reduced use of external beam radiotherapy (EBRT) for RB. Presently, tumor reduction with chemotherapy with or without focal surgery (chemosurgery) is most commonly undertaken; EBRT is avoided as much as possible and is considered only as the last treatment option prior ...

Prostate cancer is the second most common cause of cancer death in American men, with 192,289 new cases and 27,360 deaths expected in 2009.[1] While radical prostatectomy provides excellent control for clinically localized disease, approximately one-third of patients undergoing surgery will have positive surgical margins and another 9% will have seminal vesicle invasion.[2-5] Around one-third o...

ID: 1109 Title: Integral Dose in External Beam Photon Radiotherapy Integral dose is the volume integral of the dose deposited in the patient and is equal to the mean dose times the volume. The integral dose is also the area under the curve of a differential dose absolute-volume histogram. It is widely believed that IMRT increases the integral dose to normal tissues as compared to conventional r...

The verification of the dose delivered to a patient during radiation therapy is a particularly important step for ensuring treatment quality. This step, known as in vivo dosimetry can be realized using a bidimensional dosimeter named Electronic Portal Imaging Device (EPID). However, few methods enable the determination of an accurate and fully personalized 3D dose distribution for the most curr...

BACKGROUND There is a lack of prospective studies focusing on the sexual quality of life of prostate cancer patients after conformal radiotherapy (RT). OBJECTIVE To evaluate the incidence, progression, and predictive factors for erectile dysfunction (ED). DESIGN, SETTING AND PARTICIPANTS Patients who responded to the sexual domain of the Expanded Prostate Cancer Index Composite (EPIC) quest...

BACKGROUND Up to now, the role of adjuvant radiation therapy and the extent of lymph node dissection for early stage endometrial cancer are controversial. In order to clarify the current position of the given adjuvant treatment options, a systematic review was performed. MATERIALS AND METHODS Both, Pubmed and ISI Web of Knowledge database were searched using the following keywords and MESH he...

Radiobiological limitations for dose escalation in external radiotherapy are presented. Biological and clinical concept of brachytherapy boost to increase treatment efficacy is discussed, and different methods are compared. Oncentra Prostate 3D conformal real-time ultrasound-guided brachytherapy is presented as a solution for boost or sole therapy.

External beam radiotherapy (EBRT) for the treatment of loco-regional prostate cancer yields similar survival rates to radical prostatectomy (10-year survival: 90-95%, 60-70% and 50-60% in T1, T2 and T3-stages, respectively). Post-operative radiotherapy in high-risk prostate cancer may improve the local and distant disease-free survival of patients. Using the recently developed technology of the...

background: radiotherapy plays an important role in the management of most malignant and many benign primary central nervous system (cns) tumors. radiotherapy affects both tumor cells and uninvolved normal cells; so, it is important to estimate absorbed dose to organs at risk in this kind of treatment. the aim of this study was to determine the absorbed dose to chiasma, lens, optic nerve, retin...