Optimization of protein production from methanol-induced Pichia pastoris cultures is necessary to ensure high productivity rates and high yields of recombinant proteins. We investigated the effects of temperature and different linear or exponential methanol-feeding rates on the production of recombinant Fusarium graminearum galactose oxidase (EC 1.1.3.9) in a P. pastoris Mut(+) strain, under re...

  The advent of e-commerce has prompted many manufacturers to redesign their traditional channel structure by engaging in direct sales. In this paper, we present a dual channel inventory model based on queuing theory in a manufacturer-retailer supply chain, consisting of a traditional retail channel and a direct channel which stocks are kept in both upper and lower echelon. The system receives ...

the advent of e-commerce has prompted many manufacturers to redesign their traditional channel structure by engaging in direct sales. in this paper, we present a dual channel inventory model based on queuing theory in a manufacturer-retailer supply chain, consisting of a traditional retail channel and a direct channel which stocks are kept in both upper and lower echelon. the system receives st...

The purpose of the present paper is (i) to extend the stochastic models in the previous studies [1, 2 and 3] so as to analyze flow-reliability R(t) of an arbitrary coherent repairable network under periodically changing demand (t), and (ii) to prove that the flow-reliability can also be evaluated asymptotically as an exponential function under mild assumptions. In the model, flow (X(t)) o...

In this study a new approach to rank exponential fuzzy numbers using  -cuts is established. The metric distance of the interval numbers is extended to exponential fuzzy numbers. By using the ranking of exponential fuzzy numbers and using  -cuts the critical path of a project network is solved and illustrated by numerical examples. Keywords: Exponential Fuzzy Numbers,  -cuts, Metric Dista...

Several emerging communication technologies hold the key to approaching the information theoretic limits of wireless multiple access channels. This article offers a brief review of those technologies and their promise to meet future demand for wireless data rate. One of the defining features of the information technology industry is the unrelenting exponential growth of the " bandwidth, " or da...

development of potent new anti-shigella agents for rapid and specific detection and treatment is of great importance. aptamers, nucleic acid oligomers capable of specific binding to a wide range of non-nucleic acid targets, may be of value for this purpose. in the present study, we used a systematic evolution of ligands by exponential enrichment (selex) process to select dna aptamers that b...