Neuro-inflammation plays an important role in the recovery of brain injury after stroke. Microglia/macrophage is the major executor in the neuro-inflammation, which can be polarized into two distinct phenotypes: injurious/toxic classical activation (M1 phenotype) and protective alternative activation (M2 phenotype). Here, we investigated whether intracerebral administration of interleukin-4 (IL...

Many large-scale computational applications contain irregular data access patterns related to unstructured problem domains. Examples include nite element methods, computational uid dynamics, and molecular dynamics codes. Such codes are diicult to parallelize ef-ciently with current HPF compilers. However, most of these problems exhibit spatial locality. This property is exploited by our approac...

Chemoresistance prevents the curative cancer therapy, our understanding of which remains inadequate. Among the differentially expressed genes between the chemosensitive (5637) and chemoresistant (H-bc) bladder cancer cell lines, the expression level of the PSEN1 gene (presenilin 1), a key component of the γ-secretase, is negatively correlated with chemoresistance. A small interfering RNA mediat...

Current parallelizing compilers cannot extract a significant fraction of the available parallelism in a loop if it has a complex and/or statically insuficiently defined access pattern. In this paper, a run-time technique based on insp/exec scheme (inspector phase and executor phase) is proposed for finding parallelism on loops. Our inspector can determine the wavefronts of a loop with any compl...

The engineers who analyze tra c on high bandwidth networks must lter and aggregate either recorded traces of network packets or live tra c from the network itself. These engineers perform operations similar to database queries, but cannot use conventional data managers because of performance concerns and a semantic mismatch between the analysis operations and the operations supported by commerc...

Current solutions for generating Web service business processes (e.g. BPEL4WS) are generally based on centralised models, where a business process is driven by a centralised workflow engine, which schedules the work to be done and assigns it to an appropriate executor. Consequently, current solutions suffer from drawbacks (e.g., poor scalability, vulnerability to failures, etc.), caused by inad...

The algorithms and execution policies specified by the Parallelism TS are designed to permit implementation on the broadest range of platforms. In addition to preemptive thread pools common on some platforms, implementations of these algorithms may want to take advantage of a number of mechanisms for parallel execution, including cooperative fibers, GPU threads, and SIMD vector units, among oth...

The banking sector is one of the best examples who create Big Data with increasing transactions per second across the globe. Each bank is administered by the DBA (Database Administrator) as a technical in charge. DBA makes an arrangement in the branch to divert query from authorized user to the appropriate data repository. The SQL core Engine accepts input stream, processes and optimized to inc...

While network query engines make it possible to gather and combine data from multiple Web sources, these systems primarily focus on efficient query execution and do not solve some of the more complicated problems of online information gathering. Such problems require alternative types of control flow and better integration with the external world; the unique nature of the Web requires query pla...

Original scientific paper Serbia is a developing country, which among other things implies underdeveloped industrial base. A fact is that more than two thirds of all Serbian industry includes low-tech and medium-low-tech companies. These companies should implement tools and methods that are simple and low cost, but effective and helpful in a way that will increase their productivity and product...