Vaccine adjuvants are immunostimulatory substances used to improve and modulate the immune response induced by antigens. A better understanding of antigen-adjuvant interactions is necessary ...

Dendritic cells (DCs) are antigen presenting cells with unique capability to take up and process antigens in the peripheral blood and tissues. They subsequently migrate to draining lymph nodes where they present these antigens and stimulate naive T lympho-cytes. During their life cycle, DCs go through two maturation stages and are referred to as immature and mature cells, respectively. While im...

Objective(s): Detection of circulating Mycobacterium tuberculosis (M. tuberculosis) antigens is promising in Tuberculosis (TB) diagnosis. However, not a single antigen marker has been found to be widely expressed in all TB patients. This study is aimed to prepare broadly reactive polyclonal antibodies targeting multiple antigen markers (multi-target antibodies) and evaluate their efficacies in ...

The antigens of Yersinia ruckeri, Aeromonas salmonicida sp.salmonicida, Listonella anguillarum and Renibacterium salmoninarum were immunized to rainbow trout different ages immersion intraperitaneal, then waited 300 degree days, after which they infected with homologous heterologous strains the studied microorganisms. Prepared their various combinations used in experiments. After control infect...

Breast cancer (BC) is the most frequent malignant neoplasia and leading cause of mortality for women. A timely diagnosis BC crucial to ensure best chances survival. Among various screening tools BC, antibodies directed towards self-antigens or tumor-associated antigens (autoantibodies) have emerged as an alternative image-based modalities. However, little attention has been paid global diversit...

in this study one lymph node from cow with viral lymphosarcoma and one lymph node from healthy cow were analyzed by three different methods for protein extraction, include simple homogenizing in pbs, sonication and phenol extraction. tumor antigen detection relies on immunoprecipitation followed by sds-page. in this experiment streptococcus pyogenes was used for purification of immune complexes...

interleukin (il)-17 is exclusively produced by cd4 helper t-cells upon activation. it most often acts as a pro-inflammatory cytokine, which stimulates the release of pro-inflammatory cytokines il-6, il-8, tnf-α, and granulocyte-macrophage colony-stimulating factor (gm-csf). in this study, we studied the in-vitro il-17 response to specific antigens and a variety of mitogens and compared the il-1...