Block-based programming languages have lowered the threshold to computer science (CS), providing a powerful (low threshold-high ceiling) arena for early CS education and engagement in STEM subjects. This paper presents results of an empirical study three schools; involving 43 pupils aged 12‒16 using MakeCode with Microbit (a microcontroller), basic physical objects, Zoom video communication as ...

Background: Recent techniques of radiotherapy such as volumetric modulated arc therapy (VMAT) that delivered in Coplanar technique or non-coplanar allows to deliver high doses the brain tumors, at same time reducing risk normal tissues compared with intensity (IMRT) and three-dimensional conformal (3D-CRT). Aim: The aim current work is compare dosimetrical radiobiological indices treatment plan...

The performance of face verification system using linear discriminant analysis (LDA) depends on many factors such as the image geometric registration, the feature space dimensions, photometric normalisations, matching schemes adapted in the LDA subspace, etc. In this paper, the relationships among these factors were explored by illustrating experimental results obtained on a publicly available ...

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Every day, each active social network user produces and shares texts, images and videos. While developers can access such data through application programming interfaces (APIs) for creating games, visualizations and routines, end users have less control on such information. Their access is mediated by the social application features, which limits them in combining sources, filtering results and...

The acceleration of technology in business since the 1980s suggests that traditional management techniques, systems, and strategies employed in a business environment should be challenged. As a consequence of this acceleration, end-user computing (EUC) and end-user development (EUD) have also grown. Definitions of EUC developed in the 1980s continue to be used by contemporary researchers withou...

In vitro survival measurements using two human head-and-neck cancer (HNC) cell lines were performed. The specially designed split-dose surviving fraction was obtained and fitted to the linear-quadratic formalism. The repair halftime (Tr), the potential doubling time (Td), a/β and radiosensitivity a, were estimated. Other radiobiological models: EUD, BED, TCP, etc., were used to examine the pote...

BACKGROUND To evaluate and compare the biological impact on different proposed margin recipes for the same geometric uncertainties for intra-hepatic tumors with different tumor cell types or clinical stages. METHOD Three different margin recipes based on tumor motion were applied to sixteen IMRT plans with a total of twenty two intra-hepatic tumors. One recipe used the full amplitude of motio...

Objectives: Carvedilol (CVD) is a nonselective β-adrenergic blocker that suffers from low absolute bioavailability (25-35%) due to first-pass metabolism. CVD-loaded buccal tablets were developed as a promising approach to overcome this limitation. Methods: The bilayers tablets were prepared by the direct compression technique. CVD-containing layer was based on one of four high molecular weight ...

PURPOSE To demonstrate a method of generating patient-specific, biologically-guided radiotherapy dose plans and compare them to the standard-of-care protocol. METHODS AND MATERIALS We integrated a patient-specific biomathematical model of glioma proliferation, invasion and radiotherapy with a multiobjective evolutionary algorithm for intensity-modulated radiation therapy optimization to const...