Background:Continuous chelation can be defined as the concept of using a single mix weak chelator with NaOCL throughout entire root canal preparation procedure without causing reduction in antimicrobial and proteolytic activity NaOCL. Etidronic acid, also known "1-Hydroxyethylidene-1, 1-Bisphosphonate" HEBP, or HEDP, is soft biocompatible utilized direct combination sodium hypochlorite to form ...

in the treatment of Paget's bone disease. Lancet 1971 ;i: 1 139-43. 5 Smith R, Russell RGG, Bishop MC, Woods CG, Bishop M. Paget's disease of bone. Experience with a diphosphonate (disodium etidronate) in treatment. QJ7Med 1972;42:235-56. 6 Douglas DL, Duckworth T, Kanis JA, Jefferson AA, Martin TJ, Russell RGG. Spinal cord dysfunction in Paget's disease of bone. Has medical treatment a vascula...

Combination of 1 alpha(OH) D3(vit D) and ethylene glycol induced renal or ureteral stones or both consisting of calcium oxalate in male Wistar rats. This study investigates the effect of EHDP on calcium oxalate stone using the rat model. EHDP reduced the frequency of renal stone and calcium content in the kidney, and reduced the size of the stones in the renal pelvis and ureter. EHDP biochemica...

We can distinguish three generations of bisphosphonate. The first is formed of the non-aminobisphosphonate (Etidronate, Clodronate), the second correspond to the aminobisphosphonates (Pamidronate, Alendronate) that are 100 to 500 times more powerful, and the third generation (Ibandronate, Risedronate and Zoledronate) that is 10 to 20 times more powerful than the previous generations in terms of...

A female infant was delivered at term with complications of severe meconium aspiration and birth asphyxia. Surface cooling was performed in the first 24 hours as part of the management of her birth asphyxia. Woody erythema was noted at 24 hours, followed by the formation of red-purple nodules on the 6th day. Clinical findings in the first 24 hours were suggestive of cold panniculitis. However, ...

OBJECTIVE To assess the association between atrial fibrillation and flutter and use of bisphosphonates for osteoporosis among women. DESIGN Population based case-control study, using medical databases from Denmark. SETTING Northern Denmark. PARTICIPANTS 13 586 patients with atrial fibrillation and flutter and 68 054 population controls, all with complete hospital and prescription history....