PURPOSE Aldose reductase (AR) has been a drug target because of its involvement in the development of secondary complications of diabetes including cataract. Although numerous synthetic AR inhibitors (ARI) have been tested and shown to inhibit the enzyme, clinically synthetic ARIs have not been very successful. Therefore, evaluating natural sources for ARI potential may lead to the development ...

background: rosemary (rosmarinus officinalis l.) as a member of the lamiaceae family is a valuable aromatic and medicinal plant which is cultivated in large scale in iran. therefore, it is necessary to determine influence of factors affecting plant growth and drug metabolite production. objectives: this experiment was carried out to evaluate the effects of bio-stimulators compounds on growth an...

UNLABELLED PHARMACOLOGICAL RELEVANCE: Presentation of the scratch assay as a convenient and inexpensive in vitro tool to gain first insights in the wound healing potential of plant extracts and natural compounds. AIM OF THE STUDY The present study deals with the optimization of the scratch assay which can be used as an in vitro model for quantification of fibroblast migration to and prolifera...

Rosmarinus officinalis (Lamiaceae) possesses antioxidant activity and hepatoprotective effects, and so may provide a possible therapeutic alternative for chronic liver disease. The effect produced by a methanolic extract of Rosmarinus officinalis on CCl(4)-induced liver cirrhosis in rats was investigated using both prevention and reversion models. Over the course of the development of cirrhosis...

Background & Aim:Jasmonic acid (JA) is regarded as endogenous regulators that play important roles in regulating stress responses, plant growth and development.Effect of foliar application of JA on the essential oil and oil chemical components of hyssop (Hyssopus officinalis L.) were investigated. Experimental:  This study conducted in a CRD with three replications and in experimental...

Background & Aim:Jasmonic acid (JA) is regarded as endogenous regulators that play important roles in regulating stress responses, plant growth and development.Effect of foliar application of JA on the essential oil and oil chemical components of hyssop (Hyssopus officinalis L.) were investigated. Experimental:  This study conducted in a CRD with three replications and in experimental...

     Chemical constituents of the essential oil of flowers of Lavandula officinalis Chaix. growing in Isfahan, Iran, were studied by TLC and gas chromatography-mass specrtometery (GC-MS) methods. Twelve components which constitute 94.8% of the examined oil were identified. The main constituents were linalool (34.1%), 1,8-cineole (18.5%), borneol (14.5%), camphor (10.2%), terpinen-4-ol (4.5%), l...

The components of Magnolia officinalis have well known to act anti-inflammatory, anti-oxidative and neuroprotective activities. These efficacies have been sold many products as nutritional supplement extracted from bark of Magnolia officinalis. Thus, to assess and compare neuroprotective effect in the nutritional supplement (Magnolia Extract(TM), Health Freedom Nutrition LLC, USA) and our ethan...

Rosmarinus officinalis has been used in traditional medicine extensively. This study evaluated the hormonal and cellular effects of Rosmarinus officinalis extract on testes of adult rats. Thirty male Wistar rats (in three groups) received 50 or 100 mg/Kg b.w of Rosmarinus officinalis extract (made from the plant's leaves, flower and stem) (treatment groups) and 10 mL/Kg b.w normal saline (contr...

The study used bitter almonds (Amygdalus communis L. Varietas amara D.C.) obtained by cold pressing medicinal nails grown in Navoi region using oil (Calendula officinalis L.) - with the participation of flowers, extraction process was carried out maceration (in a ratio 1:10). resulting extract studied its elemental composition, chromatographic analysis fatty acids, microbiological purity, chemi...