Shields, R., Jenkins, S. A., Baxter, J. N., Kingsnorth, A. N., Ellenbogen, S. A., Makin, C.A., Gilmore, I., Morris, A. I., Ashby, D. and West, C. R. (1992) A prospective randomised controlled trial comparing the efficacy of somatostatin with injection sclerotherapy in the control of bleeding oesophageal varices. Journal of Hepatology 16, 128-137. Since previous reports have suggested that somat...

BACKGROUND Sclerotherapy has been shown to be an effective and increasingly popular therapeutic strategy for the treatment of varicose veins. However, recent reports of serious side effects, including cerebrovascular accidents (CVA) and transient ischemic attacks (TIA), as well as speech and visual disturbances, have caused serious concern regarding its use. This review evaluated the reported i...

The PROVA Study Group. (1991) Prophylaxis offirst hemorrhage from esophageal oarices by sclerotherapy, propranolol or both in cirrhotic patients: A randomized multicenter trial. The objective of this randomized multicenter trial was to assess the prophylactic effect on the incidence and severity of the first variceal hemorrhage of endoscopic sclerotherapy, propranolol and the combination of the...

OBJECTIVE The aim of the study was to determine the effectiveness of alcohol sclerotherapy in patients with human immunodeficiency virus related salivary gland disease. STUDY DESIGN Prospective study investigating the effectiveness of alcohol as a sclerosing agent. SETTING Tertiary referral hospital. PATIENTS Eleven human immunodeficiency virus positive patients with benign lymphoepitheli...

One hundred and nine patients presenting with severe haemorrhage from benign peptic ulcers were randomised to either endoscopic injection sclerotherapy using a combination of 1:100,000 adrenaline and 5% ethanolamine or to conservative treatment. Only high risk patients with active bleeding or endoscopic stigmata of recent haemorrhage and accessible ulcers were considered. The two groups were we...

67 quantitative measures of liver function remained good. These data are consistent with our own study comparing DSRS and sclerotherapy which measured quantitative liver function. We showed that patients successfully managed with sclerotherapy, who had no major rebleeding, showed a significant improvement in galactose elimination capacity over the first year1. Lesson: the data in this study sho...

Here we report successful thoracoscopic-assisted sclerotherapy of a large, prenatally diagnosed microcystic thoracoabdominal lymphatic malformation in a 3-month-old infant born at 38 weeks gestational age. Compression of the inferior vena cava and aortic displacement was demonstrated on imaging. Treatment options include medical management, percutaneous sclerotherapy, or surgical resection. The...

Endoscopic sclerotherapy has been used to control acute variceal haemorrhage which persists despite conservative therapy, prevent recurrent variceal haemorrhage in patients with a history of oesophageal haemorrhage, and to prevent a haemorrhage in patients with oesophageal varices who never bled. In this short paper I will cover our personal experience with more than 2000 patients receiving par...

Bleeding from esophageal and gastric varices remains a significant cause of morbidity and mortality for patients with liver cirrhosis. Currently, therapeutic strategies for gastric variceal bleeding include transjugular intrahepatic portosystemic shunt, cyanoacrylate sclerotherapy and hepatic transplantation. Though relatively safe and efficacious, endoscopic sclerotherapy using cyanoacrylate h...