The purpose of this study was to evaluate single nucleotide polymorphism (SNP) variants of the estrogen receptor 1 gene (ESR1) at rs2234693 and rs9340799, as well as to investigate the relationship between ESR gene polymorphisms and postmenopausal osteoporosis (OP) of the spine in Chinese women. We recruited 198 postmenopausal women with OP and 276 healthy women between May 2012 and September 2...

CCDC170 and ESR1, located at 6q25.1, were associated with breast cancer (BC) risk by genome-wide association studies. Our goal was to validate the association between CCDC170-ESR1 polymorphisms and BC risk in the population of northwestern China. A case-control study of 551 patients with BC and 577 control individuals was conducted from January 2011 to November 2014. We analyzed five BC-associa...

The New Zealand (NZ) native parrots kākāpō, kākā and kea are classified as critically endangered, endangered and vulnerable respectively. Successful reproduction of kākāpō and kākā is linked to years of high levels of fruiting in native flora (mast years). To assess a possible hormonal link between native plants and reproductive success in these parrots in mast years, we examined the ligand-bin...

Estradiol (E2) is, apart from its role as a reproductive hormone, also important for cardiac function and bone maturation in both genders. It has also been shown to play a role in insulin production, energy expenditure and in inducing lipolysis. The aim of the study was to investigate if low circulating testosterone or E2 levels in combination with variants in the estrogen receptor alpha (ESR1)...

Studies in adolescents and adults have demonstrated that polymorphisms in putative psychiatric risk genes are associated with differences in brain structure, but cannot address when in development these relationships arise. To determine if common genetic variants in disrupted-in-schizophrenia-1 (DISC1; rs821616 and rs6675281), catechol-O-methyltransferase (COMT; rs4680), neuregulin 1 (NRG1; rs3...

The Relationship between Temperament and Character Traits and Burnout among Nurses Ahmet Bulent Yazici1*, Osman Esen2, Esra Yazici1, Hayrunisa Esen3 and Mustafa Ince4 1Department of Psychiatry, Sakarya University Education and Research Hospital, Sakarya, Turkey 2Department of Anesthesia, Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey 3Department of Pediatric Surgery, Kocaeli De...

Unnamed, indistinguishable types (UITs) are a useful feature in a constraint specification language since they enable the specification of problems at a higher level of abstraction. There is, however, some debate as to the concept of UITs and their provenance. This note is intended to clarify this matter. Specifically, it describes UITs, shows that they originated in our work [1] on Essence, an...

1 Ebru Kolsal1, Ayse Serdaroglu2, Sebnem Soysal2, Esra Gurkas2, Unsal Yılmaz2 1Bakirkoy Dr. Sadi Konuk Research Hospital, Department of Pediatric Neurology, İstanbul, 2Gazi University Faculty of Medicine, Department of Pediatric Neurology, Ankara, Türkiye Oksipital Epilepsilerde Nörokognisyon / Neurocognition in Occipital Epilepsy Cognitive Findings in Benign Childhood Epilepsy with Occipital P...