Frederica de Laguna’s archaeological, ethnohistorical, and ethnographic research has provided us a rich record of the importance of metal, especially copper, to Native Alaskans. This paper provides a brief review of some of de Laguna’s thoughts on metal, its use and time of appearance in far northwestern North America. Additionally, this paper provides a discussion of the relationship between c...

Poor understanding of the causes of primary hepatitis, especially idiopathic chronic hepatitis, results in limited options for adequate treatment and variable results. Elucidating the causes, aside from the copper-associated form of hepatitis, is of utmost importance to find etiology-based treatments for canine (chronic) hepatitis, when possible, most likely resulting in a better prognosis.

We report the use of triazacyclophane (TAC)-scaffolded amino acids as a structural mimic for 3-histidine metal-binding sites in metalloproteins, especially for the mimicry of type-3 copper binding sites as are present in hemocyanin, tyrosinase and catechol oxidase.

Copper and iron play important roles in a variety of biological processes, especially when being chelated with proteins. The proteins involved in the metal binding, transporting and metabolism have aroused much interest. To facilitate the study on this topic, we constructed two databases (DCCP and DICP) containing the known copper- and iron-chelating proteins, which are freely available from th...

conclusions the elevation of hmw-alp activity in cu treated animal suggests the occurrence of biliary disease. this may be used as a biomarker for the diagnosis of copper toxicity. results obtained data showed that with increasing administration of copper, the alp activity was elevated significantly. in comparison with the control group the elevations were between 20%-56% using gel filtration c...

Copper smelting slags are hard materials. Therefore,to recover their copper by flotation method, grinding should be carried out to obtain optimal particle size. Copper smelting slags in the Bardeskan district, with work index of 16.24 kwh/st, were grinded for 65 minutes to reach an acceptable degree of freedom for the flotation tests, with particle size of 80%, smaller than 70 μm. With this gri...

tepe sagzabad, a site situated on the qazvin plain of north-central iran, was excavated from 1970 to 1998 by the institute ofarchaeology of tehran university. recent excavations by h. tala’i (1997-1999) yielded some metal artifacts dating to theearly iron age. ten of these copper-based samples were investigated using inductively coupled plasma optical emissionspectroscopy (icp-oes), scanning el...

Cuprous oxide-based antifouling paint is now the most common type in use, especially in the shipping industry. Anti-fouling paints prevent or slow down the growth of organisms attached to the hull, in order to improve a vessel’s performance and durability. However, copper is a scarce resource and never can be retrieved or recycled after leaching into the sea. The need to protect sensitive marin...

BACKGROUND Protective respiratory face masks protect the nose and mouth of the wearer from vapor drops carrying viruses or other infectious pathogens. However, incorrect use and disposal may actually increase the risk of pathogen transmission, rather than reduce it, especially when masks are used by non-professionals such as the lay public. Copper oxide displays potent antiviral properties. A p...

copper (cu) is an essential trace element involved in normal reproduction but its over-exposure may produce some detrimental effects. the aim of this study was to investigate the effects of purslane on copper sulfate poisoning on liver structures changes. twenty eight wistar rats were randomly allocated to four treatment groups. group i) control, group ii) copper sulfate (200 mg/kg bw were appl...