BACKGROUND Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal, rare hereditary disease with an estimated prevalence of 1:10 000. The genetic variants that cause CPVT are usually highly penetrant. To date, about 189 variants in 5 genes (RYR2, CASQ2, CALM1, TRND, and KCNJ2) have been associated with CPVT pathogenesis. METHODS AND RESULTS The Exome Sequencing Project databa...

Although Event Stream Processing (ESP) systems exit for already more than a decade, we recently witness a true renaisance for ESP systems that have adopted the popular MapReduce paradigm. In this white paper, we advocate for the StreamMapReduce approach as it allows a (i) quick and easy transition of legacy MapReduce-based applications to ESP, (ii) simplifies the implementation of fault toleran...

The particles emitted from diesel engine exhaust have low resistivity and extremely small in the range of 70-120nm. An electrostatic precipitator (ESP) has been extensively used for the collection of these particles. A two-stage ESP using charging section and collection section has been installed for the collection of diesel particles and improving the visibility index in road tunnels. The char...

The potential virulence factors of enterococci include production of enterococcal surface protein (Esp), gelatinase, and hemolysin. Gelatinase- and hemolysin-producing strains of Enterococcus faecalis have been shown to be virulent in animal models of enterococcal infections. Esp production has been shown to enhance the persistence of E. faecalis in the urinary bladder. We determined the presen...

1. Marrugat J, Elosua R, Gil M. Epidemiología de la muerte súbita cardiaca en España. Rev Esp Cardiol. 1999;52:717-25. 2. Maron BJ. Hypertrophic cardiomyopathy. A systematic review. JAMA. 2002;287:1308-20. 3. Peinado R, Arenal A, Arribas F, Torrecilla E, Álvarez M, Ormaetxe JM, et al. Registro Español de Desfibrilador Automático Implantable. Primer informe oficial del Grupo de Trabajo de Desfib...

1. Hearmon, C.J. & Ghosh, S.K. Listeria monocytogenes meningitis in previously healthy adults. Postgrad Med J 1989, 65: 74-78. 2. Bach, M.C. & Davis, K.M. Listeria rhombencephalitis mimicking tuberculous meningitis. Rev Infect Dis 1987, 9: 130-133. 3. Klein, N.C., Damsker, B. & Hirshman, S.Z. Mycobacterial meningitis. Retrospective analysis from 1970 to 1983. Am J Med 1985, 79: 29-34. 4. Doming...

Aligned protein a-helix dipoles have been implicated in protein function and structure. The recent breakthroughs in high-resolution electron microscopy (EM) of macromolecules makes it possible to explore fundamental aspects of structural biology at the detailed molecular level. The electrostatic potential (ESP) generated by aligned protein a-helix dipole should be observable in high-resolution ...

There is a growing interest among the higher education principals and policy makers to improve teacher evaluation methods and more important than that to use the evaluation data. A number of research studies implied the ineffective instruction of ESP courses in Iran (Atai, 2002; Eslami, 2005; Hayati, 2008; Ahmadi, 2008; Sherkatolabbasi & Mahdavi, 2012; Boniadi, Ghojazadeh & Rahmatvand, 2013). T...

PREFACE Health Services Research & Development Service's (HSR&D) Evidence-based Synthesis Program (ESP) was established to provide timely and accurate syntheses of targeted healthcare topics of particular importance to Veterans Affairs (VA) managers and policymakers, as they work to improve the health and healthcare of Veterans. The ESP disseminates these reports throughout the VA. HSR&D provid...