Esophageal cancer represents the fourth most common gastrointestinal cancer and generally confers a poor prognosis. Prostaglandin-producing cyclo-oxygenase has been implicated in the pathogenesis of esophageal cancer growth. Here we report that prostaglandin dehydrogenase, the major enzyme responsible for prostaglandin degradation, is significantly reduced in expression in esophageal cancer in ...

multiple esophageal diverticula is a rare entity that may be seen in the course of esophageal motor disorders. herein, i reported a 45 year-old man presented with intermittent chest pain and dysphagia since 20 years ago that exaggerated during the last six months. barium swallow and upper gi endoscopy revealed multiple diverticula along the esophagus and his esophageal manometry showed high amp...

esophageal cancer is the ninth most common malignancy.the incidence of esophageal cancer varies greatly among regions of the world and occurs at a high frequency in asia and northern iran. we report the case of an 80-year-old man with esophageal squamous cell carcinoma who initially presented with a metastatic scalp lesion. esophagoscopy was performed and a lesion was located in the mid-portion...

herein, we present the case of a 45-year-old woman with pulsion and midesophageal diverticula, who had complaints of dysphagia and regurgitation. diagnosis was confirmed by endoscopy and barium swallow. the patient underwent right posterolateral thoracotomy with excision of diverticula and repair of the muscular layer along the site of diverticula. five days following the operation, barium swal...

background: using bouginage or balloon dilatation is the standard treatment for benign esophageal strictures. aùžbout two-thirds need repeated dilatations. for preventing recurrent strictures, many medications such as mitomycin-c have been used. mitomycin-c is a special antibiotic with anti-neoplastic characteristics, which inhibits fibroblast proliferation, reduces collagen production and decr...

Lim DM, Narasimhan S, Michaylira CZ, Wang ML. TLR3mediated NFB signaling in human esophageal epithelial cells. Am J Physiol Gastrointest Liver Physiol 297: G1172–G1180, 2009. First published September 24, 2009; doi:10.1152/ajpgi.00065.2009.—Despite its position at the front line against ingested pathogens, very little is presently known about the role of the esophageal epithelium in host innate...

background : the age standardized incidence rates of esophageal cancer in women and men in iran have the fifth and eighth ranks, respectively. due to the high incidence rate of esophageal cancer and the necessity of knowledge of its geographical distribution, the incidence of this cancer was mapped at province and county levels in the present study. methods: the study population of this empiric...

background: esophageal cancer is the second most common malignancy in iranian men and third most common in iranian women.the aim of this study is to discover the geographic distribution for age-standardized incidence rate of esophageal cancer among both genders in iran. methods: this ecological study used re-analysis medical records aggregated to provinces from the national cancer registry and ...

● Epidemiology ● Esophageal atresia occurs in about 2.4 of every 10,000 live births, with a slight preponderance in males and children of older or diabetic mothers. Esophageal duplication cysts account for 10 to 15 percent of all foregut duplication cysts and only 5 to 10 percent of all mediastinal cysts. Congenital esophageal stenosis occurs in between 1:25,000 and 1:50,000 live births. Bochda...

Mechanisms underlying coronary spasm are still poorly understood. The aim of the study was to assess the hypothesis that fluctuations in the development of coronary spasm might reflect inputs from the adjacent esophageal system. We enrolled patients admitted to the coronary care unit for episodes of nocturnal angina. Seven patients with variant angina and five with coronary artery disease (CAD)...