RP 59500 is a new injectable streptogramin composed of two synergistic components (quinupristin and dalfopristin) which are active against a number of erythromycin-susceptible and -resistant gram-positive bacteria. The following experiments investigate the ability of RP 59500 to prevent experimental endocarditis due to either of two erythromycin-susceptible streptococcal isolates or their const...

The susceptibilities to telithromycin of 203 Streptococcus pneumoniae isolates prospectively collected during 1999 and 2000 from 14 different geographical areas in Spain were tested and compared with those to erythromycin A, clindamycin, quinupristin-dalfopristin, penicillin G, cefotaxime, and levofloxacin. Telithromycin was active against 98.9% of isolates (MICs, < or =0.5 microg/ml), with MIC...

a comparative study on the effect of erythromycin and ivermectin on abomasal emptying in holstein-friesian calves motilides namely erythromycin have a great ability to increase abomasal emptying rate. the aim of this study was to evaluate the abomasal emptying rate in calves receiving either erythromycin or ivermectin. five male holstein-friesian calves were given each of the following 4 treatm...

Erythromycin-resistant Streptococcus pneumoniae isolates from young carriers were tested for their antimicrobial susceptibility; additionally, inducibility of macrolide and clindamycin resistance was investigated in pneumococci carrying erm(A), erm(B), or mef(A). Of 125 strains tested, 101 (81%) were multidrug resistant. Different levels of induction were observed with erythromycin, miocamycin,...

Agar and broth microdilution MICs of RP 74501-RP 74502, a mixture of streptogramin antimicrobial agents that inhibited 90% of 22 Legionella strains tested, were 0.64 and 0.08 microgram/ml, respectively; respective erythromycin values were 1.0 and 0.12 microgram/ml. RP 74501-RP 74502 at 1 microgram/ml was more active than the same erythromycin concentration in a macrophage system for both L. pne...

The frequency of erythromycin resistance within group A streptococci in Sofia, Bulgaria, from 1995 to 2001 was 2.1% (26 isolates). Of this, 57.7% was macrolide-lincosamide-streptogramin (MLS) inducible, 7.7% was MLS constitutive, and 34.6% had the M phenotype. Eleven different emm sequence types were found among 25 erythromycin-resistant isolates tested. Nineteen of 26 erythromycin-resistant is...

IMPORTANCE Patients undergoing emergency procedures under general anesthesia have impaired gastric emptying and are at high risk for aspiration of gastric contents. Erythromycin has strong gastric prokinetic properties. OBJECTIVE To evaluate the efficacy of erythromycin lactobionate in gastric emptying in patients undergoing emergency surgery. DESIGN, SETTING, AND PARTICIPANTS The Erythro-E...

TO THE EDITOR: The word nightmare originates from the 13th century and is composed of night and mare, suggestive of an evil female spirit, afflicting sleepers with a feeling of suffocation, as they ride on their chests. Classified as frightening dreams that awaken the sleeper from rapid eye movement sleep, 1 nightmares impact sleep quality and are linked to various health problems. Likewise, ni...

For quite a long time, mainly due to fewer treatment options, Clindamycin have been regarded as an alternative drug effectively manage all Staphylococcus aureus infections. Strains with inducible clindamycin resistance (iMLSB phenotype) raise concerns because therapeutic failure may occur during treatment. is mostly in treating serious infections that cannot be treated by other antibiotics, it ...