INTRODUCTION Erlotinib is an inhibitor of human epidermal growth factor approved for treating non-small cell lung cancer. The aim of this prospective observational study was to determine the prevalence of adverse cutaneous reactions caused by erlotinib and assess the management of such effects. METHODS Eleven patients with lung cancer and 1 with ovarian cancer received erlotinib at a dose of ...

Background: Fixed drug eruption (FDE) is an uncommon adverse reaction to medications. Mucosal areas, particularly the male genitalia, are favored sites. To our knowledge, no study has investigated the causative agent(s) in FDE occurring on male genitals of Iranian patients. So, we conducted a study to determine the most common agents and areas of involvement in fixed genital drug eruption of ma...

Nyos maar is located in the Cameroon Volcanic Line and generates a multitude of primary and secondary hazards to the local population. For risk assessment and hazard mitigation, the age of the Nyos maar eruption provides some vital information. Since previous dating efforts using a range of techniques resulted in vastly varying eruption ages, we applied thermoluminescence (TL) methods to obtain...

Failure of eruption of primary teeth can be considered rare, especially in maxillary anterior teeth. The problem can be either mechanical obstruction of eruption or a failure of the eruption mechanism. This case report presents failure of eruption of the maxillary right deciduous central incisor in a 4-year-old girl. The unerupted primary tooth was removed surgically. The histological finding r...

During late September 1996, a major eruption took place at the NW part of the VatnajoÈkull glacier in central Iceland. The eruption was preceded by intense seismic activity, which began with a Mw ˆ 5:6 earthquake two days previously. Two very active volcanic systems, BaÂrdarbunga and GrimsvoÈtn, are situated in that area underneath the permanent ice cap. The volcanoseismic phenomena associated ...

Data collected by a pressure sensor provide new insights into the 1999 eruption of Shishaldin volcano, Unimak Island, Alaska. On 19 April 1999, after 3 months of unrest and an extended period of low-level Strombolian activity, Shishaldin experienced a Subplinian eruption (ash plume to >16 km), followed by several episodes of strong Strombolian explosions. Acoustic data from the pressure sensor ...

BACKGROUND The diagnosis of fixed 'drug' eruption is not difficult for dermatologists, but it is difficult to identify the causative agent when the patient denies ingestion of any drugs. There have been some reported cases of fixed 'food' eruption. CASE SUMMARY A 71-year-old woman experienced repeated erythema and tense bulla with a burning sensation and pruritus on the right ankle. The erupt...

DALE, V. H. 1989. Wind dispersed seeds and plant recovery on the Mount St. Helens debris avalanche. Can. J. Bot. 67: 1434-1441. Seed dispersal and plant establishment were monitored for 4 years on the debris avalanche created by the 1980 eruption of Mount St. Helens. The number of plants on the deposit increased over time to a high of almost 2 plants/m 2 by 1983. The number of species per 250-m...

OBJECTIVE To describe the eruption chronology of the first deciduous teeth in premature infants with birth weight less than 1500 g and to compare it according to gender and nutritional status at birth. METHODS Longitudinal study including 40 low birth weight premature infants of both genders. The tooth was considered erupted when the crown went through the gum and became part of the oral envi...

Ectopic eruption is the abnormal eruption of a permanent tooth that often causes root resorption of an adjacent primary tooth which can be noted during routine dental radiographic evaluation. The mesial eruption of the permanent first molar may be a local eruption problem or may indicate developmental arch circumference deficiency requiring further consideration. Early treatment is mandatory to...