نتایج جستجو برای: ergosterol 5

تعداد نتایج: 1217242  

2012
José Martín Pilar López

BACKGROUND Many animals produce elaborated sexual signals to attract mates, among them are common chemical sexual signals (pheromones) with an attracting function. Lizards produce chemical secretions for scent marking that may have a role in sexual selection. In the laboratory, female rock lizards (Iberolacerta cyreni) prefer the scent of males with more ergosterol in their femoral secretions. ...

2006
Mona N. Högberg

Ergosterol and the phospholipid fatty acid (PLFA) 18:2o6,9 are frequently used as fungal biomarkers in studies on soils, and in accordance with the ideal for biomarkers of microorganisms they are thought to turn over rapidly after cell death and lysis. These biomarkers should also show the same patterns and responses to perturbations of the studied system. Here, I report strong correlations, in...

2005

THE unique function of ergosterol as the parent substance of vitamin D made it desirable to find a colour reaction for it, by means of which it could be detected in the presence of other sterols. In searching for such a reaction, the property of formaldehyde of shifting the colour from the red into the blue part of the spectrum in the usual colour reactions of sterols [Whitby, 1923; Rosenheim, ...

2014
Fidele Tugizimana Paul A. Steenkamp Lizelle A. Piater Ian A. Dubery

Metabolomics is providing new dimensions into understanding the intracellular adaptive responses in plants to external stimuli. In this study, a multi-technology-metabolomic approach was used to investigate the effect of the fungal sterol, ergosterol, on the metabolome of cultured tobacco cells. Cell suspensions were treated with different concentrations (0-1000 nM) of ergosterol and incubated ...

Journal: :Food and Bioprocess Technology 2023

Abstract White-button ( Agaricus bisporus ) and shiitake Lentinula edodes mushrooms are widely consumed worldwide because of their organoleptic properties but also bioactive compounds such as β-glucans, ergosterol, phenolic compounds. Although these can be eaten raw food, they usually subjected to household cooking treatments, so effect on the stability molecules was evaluated in this work. The...

2012
Qing-Ping Wu Yi-Zhen Xie Zhaoqun Deng Xiang-Min Li Weining Yang Chun-Wei Jiao Ling Fang Sen-Zhu Li Hong-Hui Pan Albert J. Yee Daniel Y. Lee Chong Li Zhi Zhang Jun Guo Burton B. Yang

Due to an altered expression of oncogenic factors and tumor suppressors, aggressive cancer cells have an intrinsic or acquired resistance to chemotherapeutic agents. This typically contributes to cancer recurrence after chemotherapy. microRNAs are short non-coding RNAs that are involved in both cell self-renewal and cancer development. Here we report that tumor cells transfected with miR-378 ac...

Journal: :Genetics 2012
Aleeza C Gerstein Dara S Lo Sarah P Otto

Beneficial mutations are required for adaptation to novel environments, yet the range of mutational pathways that are available to a population has been poorly characterized, particularly in eukaryotes. We assessed the genetic changes of the first mutations acquired during adaptation to a novel environment (exposure to the fungicide, nystatin) in 35 haploid lines of Saccharomyces cerevisiae. Th...

2012
Dawoon Chung Hubertus Haas Robert A. Cramer

In mammals, hypoxia causes facilitated erythropoiesis that requires increased iron availability with established links between oxygen and iron in regulation of the transcription factor hypoxia-inducible factor. Therefore, cellular responses to hypoxia and iron starvation are linked in mammals and are host conditions that pathogens encounter during infection. In human pathogenic fungi, molecular...

Journal: :Molecular microbiology 2007
Hyeseung Lee Clara M Bien Adam L Hughes Peter J Espenshade Kyung J Kwon-Chung Yun C Chang

We investigated the effects of the hypoxia-mimetic CoCl2 in the pathogenic fungus Cryptococcus neoformans and demonstrated that CoCl2 leads to defects in several enzymatic steps in ergosterol biosynthesis. Sterol defects were amplified in cells lacking components of the Sre1p-mediated oxygen-sensing pathway. Consequently, Sre1p and its binding partner Scp1p were essential for growth in the pres...

Journal: :Fungal genetics and biology : FG & B 2011
Andrew Breakspear Matias Pasquali Karen Broz Yanhong Dong H Corby Kistler

The ortholog of the human gene NPC1 was identified in the plant pathogenic, filamentous fungus Fusarium graminearum by shared amino acid sequence, protein domain structure and cellular localization of the mature fungal protein. The FusariumNpc1 gene shares 34% amino acid sequence identity and 51% similarity to the human gene, has similar domain structure and is constitutively expressed, althoug...

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