[PDF] [Full Text] [Abstract] , September 20, 2010; . Cereb. Cortex Xiaoming Jin, John R. Huguenard and David A. Prince Epileptogenic Neocortex Reorganization of Inhibitory Synaptic Circuits in Rodent Chronically Injured [PDF] [Full Text] [Abstract] , May , 2011; 21 (5): 1094-1104. Cereb. Cortex Xiaoming Jin, John R. Huguenard and David A. Prince Epileptogenic Neocortex Reorganization of Inh...

47 Synchronization of neural oscillations is thought to integrate distributed neural 48 populations into functional cell assemblies. Epilepsy is widely regarded as disorder of 49 neural synchrony. Knowledge is scant, however, regarding whether ictal changes in 50 synchrony involving epileptogenic cortex are expressed similarly across various 51 frequency ranges. Cortical regions involved in epi...

During 1 year an 83-year-old male, with an unremarkable past medical history, was admitted six times with sudden onset of a prolonged language disorder consistent with fluent dysphasia. Showing no neurological sequelae after the first two hospitalizations, he developed an increasing residual deficit in the course of each consecutive episode. MRI studies showed repeatedly a small venous cavemoma...

In this study the role of anterior commissure was explained in the formation of secondary mirror focus during experimental temporal lobe epilepsy. The experiments were conducted on 12 adult male rabbits. Metallic cobalt powder was implanted unilaterally into basal amygdala as an epileptogenic agent. For the EEG recording bipolar electrodes of insulated nichrome wire were implanted into basal, m...

During 1 year an 83-year-old male, with an unremarkable past medical history, was admitted six times with sudden onset of a prolonged language disorder consistent with fluent dysphasia. Showing no neurological sequelae after the first two hospitalizations, he developed an increasing residual deficit in the course of each consecutive episode. MRI studies showed repeatedly a small venous cavemoma...

OBJECTIVE To present a case of intractable cryptogenic gelastic epilepsy with ictal video-EEG to localize the seizure focus. CLINICAL PRESENTATION AND INTERVENTION A 39-year-old female presented with a 2-year history of intractable gelastic epilepsy characterized by recurrent episodes of stereotyped pathological laughter, transient unresponsiveness, automatisms and brief postictal confusion. ...

Photoparoxysmal response (PPR) is commonly associated with idiopathic generalised epilepsies. Most of the focal events induced by intermittent photic stimulation (IPS) are reported to be of occipital origin. Only six temporal lobe epilepsy patients have been reported in the literature with focal PPR at extraoccipital sites. We report a four-year-old girl with possible encephalitis who presented...

Proton magnetic resonance spectroscopy ((1)H-MRS) was performed in seven healthy volunteers and 17 patients with temporal lobe epilepsy (TLE) to clarify the correlation of the severity of epilepsy with bilateral temporal changes in N-acetylaspartate (NAA), choline-containing compounds (Cho) and creatine + phosphocreatine (Cr). Despite unilateral EEG focus, bilateral temporal reduction in NAA /(...

Sir Victor Horsley, a British neurosurgeon, pioneered epilepsy surgery and, in 1886, published the reports of successful cortical resections that resulted in a significant reduction in epileptic seizures in three patients (Horsley, 1886). At that time, V. Horsley assisted by J.H. Jackson (epileptologist) and D. Ferrier (neurophysiologist), identified the region to be resected by the location of...