Head and neck squamous cell cancer (HNSCC) is the sixth leading cause of cancer-related deaths worldwide. These tumors are commonly diagnosed at advanced stages and mortality rates remain high. Even cured patients suffer the consequences of aggressive treatment that includes surgery, chemotherapy, and radiotherapy. In the past, in clinical trials, HNSCC was considered as a single disease entity...

BACKGROUND Adjuvant radiotherapy (RT) of regional lymph nodes (LN) in early breast cancer is still a matter of debate. RT increases the Overall survival (OS) rate of breast cancer patients after breast conserving surgery and after mastectomy in patients with involved LN. The contribution of RT to regional LN to this improvement was poorly identified. Recently, the results of three large randomi...

The selection of treatment options for hepatocellular carcinoma (HCC) requires critical consideration of hepatic functional reserve in addition to tumor burden (e.g., size and number of HCC nodules [tumor node metastasis stage]). Presently, the Child-Pugh classification is the most common worldwide measure used to assess hepatic functional reserve for the selection of treatment options for HCC ...

BACKGROUND AND PURPOSE To characterise the incidence, pattern and severity of post cranial radiotherapy somnolence and to identify factors predictive of frequency and severity. MATERIALS AND METHODS Seventy consecutive patients receiving radical cranial irradiation were prospectively assessed for somnolence at baseline, during and up to 10weeks following radiotherapy using five variables scor...

INTRODUCTION This study is to evaluate biochemical response, acute toxicity and health-related quality-of-life (QOL) outcomes among prostate cancer patients following stereotactic body radiation therapy (SBRT) in the first Australian CyberKnife facility. METHODS Forty-five consecutive patients with clinically localised prostate cancer were treated with SBRT using CyberKnife technology and enr...

One of the most burning problems of modern urology still remains the treatment of bladder cancer, which has the highest recurrence rate of any malignancy. Depending on a patient's individual characteristics, the probability of recurrence of non–muscle invasive bladder cancer (NMIBC) at one–year ranges from about 20% to 72% and the probability of progression at five years ranges from about 5% to...

background: we aimed to evaluate the levels of social support in patients with postoperative esophageal carcinoma and potential effect of social support on generic and ec-specific quality of life. methods: overall, 803 chinese patients with ec were recruited in the high-incidence region- linzhou in henan, china for the observation study. we obtained data on european organization for research an...