entropy as a measure of uncertainty was used to represent the results of the wavelet technique in electrochemical noise analysis. the experimental signals were obtained by recording the electrochemical potential and current noise of 7075 aluminum alloy in 3.5% nacl solution. the electrochemical potential and current noise were decomposed into 16 levels using daubechies wavelets. wavelet output ...

We extend the results of Walters on the uniqueness of invariant measures with maximal entropy on compact groups to an arbitrary locally compact group. We show that the maximal entropy is attained at the left Haar measure and the measure of maximal entropy is unique.

The structure-thermodynamics correlation analysis was performed for a series of fluorine- and chlorine-substituted benzenesulfonamide inhibitors binding to several human carbonic anhydrase (CA) isoforms. The total of 24 crystal structures of 16 inhibitors bound to isoforms CA I, CA II, CA XII, and CA XIII provided the structural information of selective recognition between a compound and CA iso...

In the present study, an analytical investigation on the entropy generation examination for viscoelastic fluid flow involving inclined magnetic field and non-linear thermal radiation aspects with the heat source and sink over a stretching sheet has been done. The boundary layer governing partial differential equations were converted in terms of appropriate similarity transformations to non-line...

The mechanism (or mechanisms) of enthalpy-entropy (H/S) compensation in protein-ligand binding remains controversial, and there are still no predictive models (theoretical or experimental) in which hypotheses of ligand binding can be readily tested. Here we describe a particularly well-defined system of protein and ligands--human carbonic anhydrase (HCA) and a series of benzothiazole sulfonamid...

Interactions at the binding interface of biomolecular complexes are often mediated by ordered water molecules. In this work, we considered two concanavalin A-carbohydrate complexes. In the first, a water molecule is buried at the binding interface. In the second, this water molecule is displaced by a modification of the ligand (Clarke, C.; Woods, R. J.; Gluska, J.; Cooper, A.; Nutley, M. A.; Bo...

Camelid nanobodies (Nbs) raised against the outward-facing conformer of a double-Trp mutant of the lactose permease of Escherichia coli (LacY) stabilize the permease in outward-facing conformations. Isothermal titration calorimetry is applied herein to dissect the binding thermodynamics of two Nbs, one that markedly improves access to the sugar-binding site and another that dramatically increas...

The effects of solvation and entropy play a critical role in determining the binding free energy in protein-ligand interactions. Despite the good balance between speed and accuracy, no current knowledge-based scoring functions account for the effects of solvation and configurational entropy explicitly due to the difficulty in deriving the corresponding pair potentials and the resulting double c...

Natural cellulose exists as a composite of cellulose forms, which can be broadly characterized as crystalline or non-crystalline. The recognition of both of these forms of cellulose by the CBMs (carbohydrate-binding modules) of microbial glycoside hydrolases is important for the efficient natural and biotechnological conversion of cellulosic biomass. The category of CBM that binds insoluble non...