Phenylalanine restriction has been used in the treatment of the metabolic and mental disorders of phenylketonuria with conflicting results. Bickel, Gerrard and Hickmans (1953) reported the first successful treatment of a child aged 31 who was observed for 12 months in hospital and at home. The biochemical abnormality of phenylpyruvic acid in the urine was corrected in this patient, but evidence...

We examined the adrenal response to handling stress of birds in different body conditions. In order to affect the birds' body condition, young (73-d old) female American kestrels (Falco sparverius) were maintained for 6 wk on one of three diets: a control diet (fed ad lib.) and two calorically restricted diets. To invoke a stress response, we removed birds from their cages and took repeated blo...

BACKGROUND The employment of dietary strategies such as ketogenic diets, which force cells to alter their energy source, has shown efficacy in the treatment of several diseases. Ketogenic diets are composed of high fat, moderate protein and low carbohydrates, which favour mitochondrial respiration rather than glycolysis for energy metabolism. DESIGN This review focuses on how oncological, neu...

Two experimental models were tried in young malnourished rats in order to study effect of an hyperosmolar challenge in the small intestine on the bi-directional fluxes of sodium. Weanling rats were fed with energy restricted diets. In model I 1 mL of NaCl 900 mOsm/kg was introduced in the small intestine of the rats and left from 5 up to 70 min, in order to determine the moment of higher net Na...

Today, obesity is one of the major health problems, a so-called epidemic of the developed world. Obesity arises through an imbalance between energy intake and energy expenditure, so it is important for products to have a balanced nutritional composition. The aim of this study is to prepare high-protein pasta with high nutritional quality, with emphasis on its amino acid composition, as ordinary...

BACKGROUND Low-energy-density diets are associated with higher diet costs per 10 MJ. Are diets of higher nutritional quality also associated with higher costs per 10 MJ? OBJECTIVE The objective was to determine the relations between energy-adjusted diet costs, dietary energy density, and nutritional quality of diets. DESIGN This was a cross-sectional study of a nationally representative sam...