Topiramate (TPM) is a novel neurotherapeutic agent currently indicated for the treatment of epilepsy and undergoing development for other central nervous system indications including neuropathic pain, bipolar disorder, and migraine prophylaxis. TPM is synthesized from D-fructose and contains a sulfamate moiety that is essential for its pharmacologic activity. TPM has been observed to significan...

The observation of jet quenching and associated away–side Mach cone– like correlations at RHIC provide powerful “external” probes of the sQGP produced in A+A reactions [1], but it simultaneously raises the question where the jet energy was deposited. The nearly perfect bulk fluidity observed via elliptic flow suggests that Mach cone–like correlations may also be due to rapid local equilibration...

We generalize the conventional model of two-dimensional site percolation by including both (1) continuous deposition of particles on a two-dimensional substrate, and (2) diffusion of these particles in two-dimensions. This new model is motivated by recent thin film deposition experiments using the low-energy cluster beam deposition (LECBD) technique. Depending on various parameters such as depo...

This paper proposes a hybrid hyperthermia treatment system, utilizing two noninvasive modalities for treating brain tumors. The proposed system depends on focusing electromagnetic (EM) and ultrasound (US) energies. The EM hyperthermia subsystem enhances energy localization by incorporating a multichannel wideband setting and coherent-phased-array technique. A genetic algorithm based optimizatio...

We have calculated the electron energy deposition distribution in Calixarene negative resist and analyzed the development profile in order to improve the resolution of pattern. From the trajectories and energy deposition distribution in resist at various beam diameters, it is obvious that the thinner resist film should be adopted for formation of very fine dots. The analysis of relationship bet...

Additive Manufacturing (AM) is the process of joining materials by selectively depositing them layer upon for purpose manufacturing parts or assemblies which are based on a 3D digital model. The nature these processes results in morphing complex component geometries, enabling high degree design freedom and resulting lightweight structures with increased performance. These processes, however, ex...

We have studied the photoluminescence of highly transparent and c-axis oriented ZnO thin films grown on (0001) sapphire by Pulsed Laser Deposition at different temperatures ranging from 10K to 300K. We observed temperature dependent recombination from free excitons, bound excitons and LO phonon assisted free and bound excitonic transitions. The energies of free excitonic transitions are close t...

I. Food intake and rates of protein, lipid and energy deposition during growth were measured for lean and congenitally obese (fatty) Zucker rats offered from 34 d of age to slaughter at 66 d of age, one of six semi-synthetic diets containing casein (C) in the following amounts (g Clkg): 40C, moC, 150C, 3wC, 500C and 700C. 2. In Expt I, groups of four male rats were offered each diet to appetite...