background and aims: mental disorders may negatively affect on the quality of life in hemodialysis patients and their response to treatment. the aim of present study was to examine the prevalence of depression and related risk factors in hemodialysis patients. methods: in this cross-sectional study, during june 2013 to september 2013, 217 patients with hemodialysis whom were admitted to kerman ...

Disturbances in Ca(2+) homeostasis and mitochondrial dysfunction have emerged as major pathogenic features in familial and sporadic forms of Amyotrophic Lateral Sclerosis (ALS), a fatal degenerative motor neuron disease. However, the distinct molecular ALS-pathology remains unclear. Recently, an activity-dependent Ca(2+) homeostasis deficit, selectively in highly vulnerable cholinergic motor ne...

background: recent interests have mainly focused on the roles of serum calcium and phosphorus and their product (ca-p product) in the development of valvular heart disease. the present study assessed the relationship between the ca-p product and the severity of valvular heart disease in end-stage renal disease (esrd) patients undergoing chronic hemodialysis. methods: this cross-sectional study ...

each year, over a billion muslims fast worldwide during the month of ramadan.  through this religious practice, not only will one have spiritual growth, but can improve his/her diet, which is of pivotal importance in this month. conversely, the available evidence regarding the health benefits of ramadan fasting is scarce and highly contentious. although islam exempts patients from fasting, many...

background considering the significant geographical and ethnical differences in pattern of incidence, etiology and outcome of chronic kidney disease (ckd), the present study aimed to assess the etiology and outcome of ckd in iranian children. materials and methods in a cross-sectional study etiology and outcome of 372 children aged 3 months to 18 years with ckd was studied during the period 199...

conclusions literature search revealed an increased prevalence of hypothyroidism with secondary hpth from renal failure. although there is increased prevalence of hypothyroid state in secondary hpth from renal failure, the association appears much weaker in primary hpth and again no conclusive pathological relation has been identified between the two endocrine glands. a closer look and perhaps ...

The burden of chronic kidney disease (CKD) and endstage kidney disease (ESKD) presents a challenge for both developed and emerging countries. While dialysis and transplantation consumes an ever-increasing proportion of the health budget in countries such as the United States, Japan and Taiwan, there is limited availability of these expensive therapies in the majority of emerging countries and e...

background: the prevalence of vitamin d deficiency is higher in end-stage renal disease (esrd) patients compared to healthy populations. this deficiency could lead to several complications with different mechanisms and might result in reduced survival in patients. leptin and adiponectin are messenger proteins with endocrine secretion from adipocytes and various effects in cellular mechanisms. t...

The ultimate aim of biomedical research is to preserve health and improve patient outcomes. However, by a variety of measures, preservation of kidney health and patient outcomes in kidney disease are suboptimal. Severe acute kidney injury has been treated solely by renal replacement therapy for over 50 years and mortality still hovers at around 50%. Worldwide deaths from chronic kidney disease ...

background the invention of central venous catheters (cvc) for hemodialysis (hd), brought about a fundamental change in the treatment of patients who needed hd, from the late 1970’s till the present time. nowadays the use of cvc is a common medical procedure. increasing use of these methods necessitates clarification of the exact nature of the effects, and potential complications for surgeons. ...