Oxidative stress has been postulated to play important roles in the pathogenesis of various diseases such as atherosclerosis in hyperlipidemic subjects. Although the possible role of oxidation of low-density lipoprotein (LDL) in the etiology of atherosclerosis has been studied extensively, the turnover of endogenous antioxidants, which is an important protection system against oxidative stress,...

Chronic obstructive pulmonary disease (COPD) is associated with a high incidence of morbidity and mortality. Cigarette smoke-induced oxidative stress is intimately associated with the progression and exacerbation of COPD and therefore targeting oxidative stress with antioxidants or boosting the endogenous levels of antioxidants is likely to have beneficial outcome in the treatment of COPD. Amon...

Cisplatin is widely used for the chemotherapy of head and neck cancer. However, it has a significant ototoxicity. Nigella sativa been scientifically proven to have numerous benefits included prevent adverse effect drug. This literature review aimed evaluate protective role N. oil against cisplatin-induced Relevant publications were searched from PubMed Google Scholar databases within last 10 ye...

Abstract The increase in the formation of reactive oxygen and nitrogen species endogenous or exogenous origin causes oxidative stress due to pro-oxidant antioxidant imbalance that cellular damage metabolism. This can inflammation cells, apoptosis necrosis, DNA base damage, protein cross-links, lipid membrane peroxidation, mitochondrial dysfunction. Antioxidants be described as a system protects...

O xidation processes are essential in normal cell metabolism. Free radicals, i.e. reactive oxygen and nitrogen compounds, are formed continuously. They participate in metabolic and cell signalling pathways, in spite of their potentially deleterious effects. A system of endogenous anti-oxidative compounds and systems operates to control strictly the concentrations and actions of free radicals. D...

The use of conventional contrast media for diagnostic purposes (in particular, Gd-containing and iodinated agents) causes a large number complications, the most common which is contrast-induced nephropathy. It has been shown that after exposure to agents, oxidative stress often occurs in patients, especially people suffering from various diseases. Antioxidants human body can diminish pathologic...

nowadays, huge tendency to fashion and consumerism could be assumed as the origin of identitycrisis among women and in their houses. this phenomenon is like a veil between man and the fact of his human being. given that the physical properties of man-made environments (house) are influenced by human properties and, in return, have an important role in giving identity to their audience, identifi...

THE EFFECTS OF REACTIVE OXYGEN SPECIES ON INTERNODAL MYELIN STRUCTURE, AND ROLE OF PLASMALOGEN PHOSPHOLIPIDS AS ENDOGENOUS ANTIOXIDANTS By: Adrienne Marie Luoma Advisor: Daniel A. Kirschner, Ph.D. Reactive oxygen species (ROS) are implicated in a range of degenerative conditions, including aging, neurodegenerative diseases, and neurological disorders such as multiple sclerosis. Myelin is a lipi...

Oxidative stress is suggested to be central to the ageing process, with endogenous antioxidant defence and repair mechanisms in place to minimize damage. Theoretically, supplementation with exogenous antioxidants might support the endogenous antioxidant system, thereby reducing oxidative damage, ageing-related functional decline and prolonging life- and health-span. Yet supplementation trials w...