BACKGROUND Anal fissure is perpetuated by high sphincter pressures and secondary local ischaemia. Pharmacological approaches include topical nitrates and botulinum toxin (BT) which act to reduce anal pressure. BT lowers anal pressure by preventing acetylcholine release from nerve terminals while topical nitrates act by donating nitric oxide (NO). The aims of the present study were to compare th...

Background—Anal fissure is perpetuated by high sphincter pressures and secondary local ischaemia. Pharmacological approaches include topical nitrates and botulinum toxin (BT) which act to reduce anal pressure. BT lowers anal pressure by preventing acetylcholine release from nerve terminals while topical nitrates act by donating nitric oxide (NO). The aims of the present study were to compare th...

purpose: to evaluate the efficacy of silicone oil injection after deep vitrectomy in infectious endophthalmitis regarding visual acuity. methods: this single-blind randomized clinical trial was performed on 50 cases of infectious endophthalmitis undergoing deep vitrectomy. patients were randomly assigned to two groups: in one group silicone oil was injected into the eye at the end of the operat...

BACKGROUND Regenerative medicine, including cell therapy, is a promising strategy for recovery of the damaged myocardium. C-kit-positive cardiac stem cells (CSCs) have been shown to improve myocardial function after ischemic injury in animal models and in early clinical experience. We used a chronic large animal model of myocardial infarction with substantial reductions in left-ventricular (LV)...

  Abstract   Background : Although, different studies on end-to-side nerve repair, results are controversial. The importance of this method in case is unavailability of proximal nerve. In this method, donor nerves also remain intact and without injury. In compare to other classic procedures, end-to-side repair is not much time consuming and needs less dissection. Overall, the previous studies i...

PURPOSE To evaluate the change in intraocular pressure (IOP) and central corneal thickness (CCT) of children who underwent congenital cataract surgery with injection of triamcinolone acetonide into the anterior chamber at the end of the procedure. METHODS Fifty-three eyes of 34 children <2 years of age who underwent congenital cataract surgery with injection of 1.2 mg/0.03 mL of preservative-...

the most accepted method of secondary prophylaxis in rheumatic fever (rf) has been an injection of 1,200,000 units of benzathine penicillin g (bpg) every 4 weeks, but recurrences have been reported in some patients despite such a prophylaxis program. the who recommended bpg injections every 3 weeks in high risk patients and situations due to some published data in favor of inadequacy of once ev...

background: the aim of this study was to evaluate the effect of chronic injection of morphine on infection with leishmania major (l. major) in sensitive balb/c and resistant c57bl/6 mice. methods: morphine injections (2 times /day with 12 hrs intervals, s.c) were begun one week before parasite inoculation. the first group of mice strains was infused with 1.5mg/kg morphine, the second group with...

OBJECTIVE Crystalline NPH insulin comes in a two-phase solution with either a solvent or a rapid-acting insulin (in premixed formulations) and needs adequate mixing for complete resuspension before injection. The aim of this study was to establish pharmacokinetics (PK) and pharmacodynamics (PD) after injection of appropriately resuspended versus nonresuspended NPH insulin. RESEARCH DESIGN AND...