Natural killer (NK) cells play an important role in innate immunity and in mediating antibody and Icon (an antibody-like factor VII/IgG1 Fc immunoconjugate, which, to our best knowledge, was the first therapeutic agent for dual targeting of both the tumor cells and tumor angiogenic endothelial cells) for cancer immunotherapy. However, a common yet often neglected observation and challenge in an...

This study investigated usability of graphical icons in the design of human–computer interfaces. A simple additive model of icon acquisition time, including terms for Index of Difficulty, mode of icon array, and log2 (number of icons) explained 95% of the variance in mean times covering all 36 conditions over 4 laboratory experiments conducted in the study. The acquisition of icons in graphical...

Engaging communication of complex scientific concepts with the general public requires more than simplification. Compelling, relevant, and timely points of linkage between scientific concepts and the experiences and interests of the general public are needed. Pop-culture icons such as superheroes can represent excellent opportunities for exploring scientific concepts in a mental “landscape” tha...

Icons are a very important component of graphical user interfaces. However, icon design is still predominantly artistic in nature and as a result icon selection is generally based on usability evaluations after a set of alternative icons are developed. This process tends to be time-consuming and costly. In this research, we address the issues of what should be depicted in an icon, given the fun...

The aims of this study were two-fold. First to compare the perceptions of African dental aesthetics as determined by a panel of black African Senegalese and French Caucasian judges, and second to compare the sensitivity and specificity of both components of the Index of Orthodontic Treatment Need (IOTN) and the Index of Complexity, Outcome and Need (ICON) in relation to the opinions of African ...

Introduction. The assessment of orthodontic treatment need and complexity are necessary for informed planning of orthodontic services. The aim of this cross-sectional study was to assess these parameters using the Index of Complexity, Outcome, and Need (ICON) in a Nigerian adolescent population in a region where orthodontic services are just being established. Methods. Six hundred and twelve ra...

The graphical user interface has brought great values in the field of human computer interface. However, the conventional GUI is more mechanical and does not recognize or communicate emotions. The modern GUIs are trying to infer the likely emotional state and personality of the user and communicate through a corresponding emotional state. Emotions can be expressed in graphical icons, sounds, pi...

Pictorial images are icons as well as eye-cons: they provide distillations of objects or ideas into simpler shapes. They create the impression of representing that which cannot be presented. Even at the level of the photograph, the links between icon and object are tenuous. The dimensions of depth and motion are missing from icons, and these alone introduce all manner of potential ambiguities. ...

where values contains the strings to be written. (In Version 9 of Icon, this form of invocation can be used with records as well as lists; we’ll just refer to lists in what follows.) The main advantage of invocation with an Icon list is that it allows the number of arguments to be determined when the program is run. This is useful primarily for built-in functions like write() and DrawLine() tha...

Our solution is given below. First we need procedures analogous to the procedure used for modeling string scanning. In addition to a subject, there’s now an “object”, which is the result of string synthesis. There now also are two positions, one in the subject and one in the object. The global identifiers subject, object, s_pos, and o_pos are used for these four “state variables” in the procedu...