PURPOSE There is a need to broaden protective coverage of M protein-based vaccines against group A streptococci (GAS) because coverage of the current 30-valent M protein vaccine does not extend to all emm types. An additional GAS antigen and virulence factor that could potentially extend vaccine coverage is M-related protein (Mrp). Previous work indicated that there are three structurally relat...

OBJECTIVES To assess the epidemiology, antibiotic resistance and genotypic characterization of group A streptococci (GAS) in Jinju, Korea. METHODS Isolates were characterized in terms of their antibiotic resistance, the phenotypes of erythromycin resistance, the frequencies of erm(B), erm(A) and mef(A) genes, and by emm genotyping or M typing. The data were compared with those from 85 GAS str...

To determine whether growth phase affects the expression of mga and other virulence-associated genes in the group A streptococcus (GAS), total RNA was isolated from the serotype M6 GAS strain JRS4 at different phases of growth and transcript levels were quantitated by hybridization with radiolabeled DNA probes. Expression of mga (which encodes a multiple gene regulator) and the Mga-regulated ge...

PURPOSE In Part 1 of this two-part work, predictions for light transport in powdered-phosphor screens are made, based on three distinct approaches. Predictions of geometrical optics-based ray tracing through an explicit microscopic model (EMM) for screen structure are compared to a Monte Carlo program based on the Boltzmann transport equation (BTE) and Swank's diffusion equation solution. The p...

Geospatial software tools (GIS) are used for creating, viewing, managing, analyzing, and utilizing geospatial data. Geospatial data can include socio-economic, environmental, geophysical, and technical data about the Earth and societal infrastructure and it is pivotal in environmental modeling and management (EMM). Desktop, web-based, and embedded geospatial tools and systems have become an ess...

Antrochoanal polyp (ACP) are benign lesions that originate from the mucosa of maxillary sinus, and extend into nasal cavity to reach choana nasopharynx. The treatment ACP is surgical, endoscopic medial maxillectomy (EMM) one options for surgical therapy. generally affects adolescents but in this case by adults. To report analyze adult patient with EMM technique. A 45-year-old man an completely ...

Abstract. The principles and major steps of Enterprise Meta-Model (EMM) based development of Use Case model (UCM) in CASE system environment are presented in this paper. The Enterprise Meta-Model represents the key concepts of domain knowledge. The enterprise processes, management functions, and their interactions are considered as the critical components of the domain knowledge accumulated as ...

Clustering streams of continuously arriving data has become an important application of data mining in recent years and efficient algorithms have been proposed by several researchers. However, clustering alone neglects the fact that data in a data stream is not only characterized by the proximity of data points which is used by clustering, but also by a temporal component. The extensible Markov...

In this article, we propose a technique called Energy Mixture Model (emm) for classification. emm is a type of feed-forward neural network that can be used to decide the number of nodes for constructing the hidden layer of neural networks based on the variable clustering method. Additionally, energy combination method is used to generate the recognition pattern as the basis for classification. ...