The "14-day rule" for embryo research stipulates that experiments with intact human embryos must not allow them to develop beyond 14 days or the appearance of the primitive streak. However, recent experiments showing that suitably cultured human pluripotent stem cells can self-organize and recapitulate embryonic features have highlighted difficulties with the 14-day rule and led to calls for it...

It is difficult to harmonise faith and the desire to follow religious teachings and obligations on the one hand, and scientific advances and their use for the benefit of suffering humanity on the other. This is an especially delicate matter for patients and health professionals in reproductive medicine. It deals with the conflicting issues of contraception, termination of pregnancy, assisted re...

Amendment text: SEC. 509. (a) None of the funds made available in this Act may be used for-(1) the creation of a human embryo or embryos for research purposes; or (2) research in which a human embryo or embryos are destroyed, discarded, or knowingly subjected to risk of injury or death greater than that allowed for research on fetuses in utero under 45 CFR 46.204(b) and section 498(b) of the Pu...

* Published with the approval of the Director of the Wisconsin Agricultural Experiment Station. Supported in part by grants from the Rockefeller Foundation, and the Research Committee of the Graduate School from funds supplied by the Wisconsin Alumni Research Foundation. 1 Wilson, P. W., Hull, J. F., Burris, R. H., PROC. NATL. ACAD. Sci., 29,289-294 (1943). 2 Rosenblum, E. D., and Wilson, P. W....

IGF1 plays an important role in bovine follicular growth, acquisition of oocyte competence and embryo viability. Current data also indicate a critical role for IGF1 in both the ovarian response and the embryo yield following the superovulatory treatments. IGF1 can have either positive or negative effects on embryo viability which is related to the concentration of IGF1 induced by superovulation...

the use of donated embryos has offered hope for infertile couples who have no other means to have children. in iran, fertility centers use fertile couples as embryo donors. in this paper, the advantages and disadvantages of this procedure will be discussed. we conclude that embryo-donation should be performed with frozen embryos thus preventing healthy donors from being harmed by fertility drug...

Questions about the relevance of religious views to public policy have been central in debates over the governance of biotechnology since the 1960s. This article offers an empirical analysis of moments of deliberative politics surrounding human embryo research, primarily within public bioethics bodies. I examine how these bodies have used the idea of public reason as developed in deliberative d...

This paper provides an overview of the ethical issues in the international clustered regularly interspaced short palindromic repeats (CRISPR) genome editing debate from March 2015 to September 2016. We present the regulatory framework for embryo research in the UK, and explain why CRISPR is not a significant break with the past. We discuss the ethical issues arising from CRISPR applications bey...

Guidelines for the safe international movement of livestock embryos are provided in the International Animal Health Code of the Office International des Epizooties, and recommendations for embryo processing, based on numerous research papers on embryo-pathogen interaction studies, are given in the Manual of the International Embryo Transfer Society. Risk assessment is the logical extension of t...