BACKGROUND Simulation-based learning is a common educational tool in health care training and frequently involves instructional designs based on Experiential Learning Theory (ELT). However, little research explores the effectiveness and efficiency of different instructional design methodologies appropriate for simulations. The aim of this study was to compare 2 instructional design models, ELT ...

Seam cells in Caenorhabditis elegans provide a paradigm for the stem cell mode of division, with the ability to both self-renew and produce daughters that differentiate. The transcription factor RNT-1 and its DNA binding partner BRO-1 (homologues of the mammalian cancer-associated stem cell regulators RUNX and CBFβ, respectively) are known rate-limiting regulators of seam cell proliferation. He...

The present study is an attempt to investigate the way culture is addressed in ELT in Iran in general and the place of culture in ELT at the high school level of education in particular. Throughout the study, this issue was examined with reference to the relevant theoretical background, and the content analysis of prescribed English textbooks. The research findings make it clear that the curren...

Gene regulation during development is an important biological activity that leads to synthesis of biomolecules at specific locations and specific times. The single tropomyosin gene of Caenorhabditis elegans, tmy-1/lev-11, produces four isoforms of protein: two from the external promoter and two from the internal promoter. We investigated the internal promoter of tropomyosin to identify sequence...

Cis-regulatory elements (CREs) are crucial links in developmental gene regulatory networks, but in many cases, it can be difficult to discern whether similar CREs are functionally equivalent. We found that despite similar conservation and binding capability to upstream activators, different GATA cis-regulatory motifs within the promoter of the C. elegans endoderm regulator elt-2 play distinctiv...

This paper reports on an analysis of the change caused by an e-textbook implementation in a school in South Africa. The PSIC model, a change model from ICT enabled change in organisations, was considered because it affirms existing educational research, but also extends it by recognising the episodic nature of change. On a vertical level the model allowed the researchers to identify and disting...

Erlotinib (ELT) as a small molecule with poor solubility, poor bioavailability, and instability in gastrointestinal environment, has been considered as a therapeutic agent for Non-Small-Cell Lung Cancer (NSCLC) therapy through oral administration. In the present study, ELT-liposome and ELT-NLCs were successfully prepared and characterized by assessment of the particle size, zeta potential (ZP),...

Introduction: Endovenous laser treatment (ELT) is a new treatment method for the reflux of the great saphenous vein. A successful ELT is dependent on the selection of optimum parameters required to achieve optimal vein damage while avoiding side effects including skin burns. The mathematical modeling of ELT can be used to understand the process of ELT. This study was conducted to examine the ef...