The interaction with iodine metabolism following ingestion of Allium cepa (onion) and Allium sativum (garlic) by albino Wistar rats have been studied. The determination of the effect of the oral administration of onion and garlic extract on thyroid hormones (triidothyronine,T3, thyroxine,T4 were studied. The mean values of triiodothyronine (T3) for the experimental animals were 1.23 ± 0.09ng/ml...

Antimicrobial sensitivity tests were carried out on Escherichia coli, Shigella sp, Salmonella sp, and Proteus mirabilis using standard procedures. Significant differences (p < 0.01) were seen in the effect of the antimicrobial agents (garlic, ciprofloxacin and ampicillin), and in the sensitivities of the microbial species (p < 0.01) to the antimicrobial agents were observed. The gram-negative d...

In this study, we aimed to confirm the protective effects of garlic saponins against oxidative stress-induced cellular damage and to further elucidate the underlying mechanisms in mouse-derived C2C12 myoblasts. Relative cell viability was determined by 3-(4.5-dimethylthiazol-2-yl)-2.5 diphenyltetrazolium bromide assay. Comet assay was used to measure DNA damage and oxidative stress was determin...

The Asian citrus psyllid, Diaphorina citri Kuwayama, vectors Candidatus Liberibacter asiaticus (Las) and Candidatus Liberibacter americanus (Lam), the presumed causal agents of huanglongbing. D. citri generally rely on olfaction and vision for detection of host cues. Plant volatiles from Allium spp. (Alliaceae) are known to repel several arthropod species. We examined the effect of garlic chive...

Ultraviolet (UV) irradiation generates reactive oxygen species (ROS) in the cells, which induces the cellular senescence and photoaging. The present study investigated the protective effects of garlic on photo-damage and cellular senescence in UVB-exposed human keratinocytes, HaCaT cells. An in vitro cell free system was used to examine the scavenging activity of 2,2-diphenyl-1-picrylhydrazyl (...

The aim of present study was to investigate the antioxidant enzymes activity and oxidative status of Cinnamon and Garlic – treated rats. 12 male Wistar Albino rats were randomly divided into 3 groups (n=4). Group I: Control rats received distilled water; Group II: Received aqueous extract of Cinnamon (10 mg / kg b.w.) orally for 13 consecutive days; Group III: Received aqueous extract of Garlic...

BACKGROUND Gentamicin (GM) nephrotoxicity has been related to oxidative stress. Garlic and metformin (MF) have anti-oxadant activity and therefore, this study was aimed to evaluate the preventive and curative effects of garlic, MF and their combination on GM indeced tubular toxicity in Wistar rats. METHODS In a pre-clinical study, 70 male Wistar rats were randomly designated into 7 groups of ...

In order to determine the impact of garlic on total cholesterol (TC), TAG levels, as well as LDL and HDL, and establish if any variables have an impact on the magnitude of this effect, a meta-analysis was conducted. A systematic literature search of MEDLINE, CINAHL and the Cochrane Database from the earliest possible date through to November 2007 was conducted to identify randomised, placebo-co...

The aim of this investigation was to evaluate the dose-dependent influence of commercial garlic on rats fed cholesterol-containing diets. It was found that commercial garlic contains high concentrations of dietary fibers, microelements, and total polyphenols, and its total antioxidant capacity as determined by two independent assays [1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azinobis(3-ethy...

Garlic (Allium sativum) is used worldwide in cooking and industry, including pharmacology/medicine and cosmetics, for its interesting properties. Identifying redundancies in germplasm blanks to generate core collections is a major concern, mostly in large stocks, in order to reduce space and maintenance costs. Yet, similar appearance and phenotypic plasticity of garlic varieties hinder their mo...