Opening of individual exocytotic fusion pores in chromaffin cells was imaged electrochemically with high time resolution. Electrochemical detector arrays that consist of four platinum microelectrodes were microfabricated on a glass coverslip. Exocytosis of single vesicles containing catecholamines from a cell positioned on top of the array is detected by the individual electrodes as a time-reso...

The presence of H2S ( hydrogen sulphide ) gas in oil and gas exploration can give rise to critical safety problems because of its corrosivity and toxicity. In order to protect people and equipment, there is a need for a real-time,remote and reliable seneor that can detcet the concentration of H2S gas. The best way to monitor H2S gas concentration is optical-electrochemical sensor technology. At...

Microfabricated devices for the electrochemical detection of single DNA base changes in cancer cell lines are highly desirable due to the inherent advantages such as portability, simplicity, and the rapid and inexpensive nature of electrochemical readout methods. Moreover, molecular sensors that use microscale-footprint working electrodes have shown high signal-to-noise ratio. Herein we report ...

Diamond is a material of interest due to its unique combination of properties, including its chemical inertness and biocompatibility. Polycrystalline diamond (poly-C) has been used in experimental biosensors that utilize electrochemical methods and antigen-antibody binding for the detection of biological molecules. Boron-doped poly-C electrodes have been found to be very advantageous for electr...

background : the recognition of road traffic noise as one of the main sources of environmental pollution has led to develop models that enable to predict noise level from fundamental variables. traffic noise prediction models are required as aids for designing roads and highways. in addition, sometimes are used in the assessment of existing or envisaged changes in traffic noise conditions. in t...