Positively charged trimethylammonium-functionalized mixed monolayer protected clusters (MMPCs) bind DNA through complementary electrostatic interactions, resulting in complete inhibition of DNA transcription of T7 RNA polymerase. DNA was released from the nanoparticle by intracellular concentrations of glutathione, resulting in efficient transcription. The restoration of RNA production was dose...

We have considered X-ray radiation of a relativistic charged particle moving in a system consisting of microspheres distributed randomly in a dielectric material. A new mechanism based on the diffusional scattering of pseudophotons is suggested. The result leads to a stronger dependence of radiation intensity on the particle energy, γ = E/mc, than that predicted by the traditional transition ra...

Insulin is released from pancreatic β-cells as a result of Ca²⁺-evoked exocytosis of dense-core granules. Secretion is biphasic, which has been suggested to correspond to the release of different granule pools. Here we review and carefully reanalyze previously published patch-clamp data on depolarization-evoked Ca²⁺-currents and corresponding capacitance measurements. Using a statistical mixed-...

Targeted delivery of nanoscale carriers containing packaged payloads to the central nervous system has potential use in many diagnostic and therapeutic applications. Moreover, understanding of the bio-interactions of the engineered nanoparticles used for tissue-specific delivery by non-invasive delivery approaches are also of paramount interest. Here, we have examined this issue systematically ...

It is important to understand the adsorption mechanism of chemicals and active pharmaceutical ingredients (API) on sewage sludge since wastewater treatment plants are the last barrier before the release of these compounds to the environment. Adsorption models were developed considering mostly hydrophobic API-sludge interaction. They have poor predictive ability, especially with ionisable compou...

Abstract The modification in the Cu 2 Se thermoelectric system by electron beam irradiation has been carried out this work. Samples were prepared using solid-state reaction technique. samples irradiated with various energy dosages viz. 50, 100, and 150 kGy. XRD studies reveal that synthesized crystallized a monoclinic structure. micro-hardness of decreased an increase dosage. sample at 100 kGy ...

The temperature-frequency dependences of: electrical conductivity (sigma(μ,T)), the real and imaginary parts of complex permittivity (ε'(ν,T)) (ε''(ν,T)), impedance TlSe compound when exposed to various doses gamma radiation. process occurrence concentration polarization at boundary ion conductor blocking contact is investigated. temperature-frequency-dose interval ionic Warburg has been establ...

Transcranial electrical stimulation (tES) encompasses all forms of research and clinical applications of electrical currents to the brain noninvasively using (at least one) electrodes on the head. The dose of tES is defined by the electrode montage and the stimulation waveform applied to the electrode [1]. There has been a resurgence of interest since 2000, but “modern” tES developed incrementa...

In this work, the photocatalytic disinfection of Escherichia coli (E. coli) using dual layer ceramic wafers, prepared by a simple and low-cost technique, was investigated. Heterojunction wafers were prepared by pressing TiO2 and WO3 powders together into 2 layers within a single, self-supported monolith. Data modelling showed that the heterojunction wafers were able to sustain the formation of ...

Based on the dual-superconductor picture, we study the confinement physics in QCD in terms of the monopole in the maximally abelian (MA) gauge using the SU(2) lattice QCD. In the MA gauge, the off-diagonal gluon component is forced to be small, and hence microscopic abelian dominance on the link variable is observed in the lattice QCD for the whole region of β. ¿From the gluon-propagator analys...