The emerging tick-borne zoonoses human monocytic ehrlichiosis (HME) and human granulocytic ehrlichiosis (HGE) are under reported in the United States. From 1986 through 1997, 1,223 cases (742 HME, 449 HGE, and 32 not ascribed to a specific ehrlichial agent) were reported by state health departments. HME was most commonly reported from southeastern and southcentral states, while HGE was most oft...

Canine tick borne disease, such as anaplasmosis and ehrlichiosis are common diseases in veterinary practices. Most patients are diagnosed using clinical findings, history of tick bites and hematological findings; however, proper approach to diagnostic is not always feasible. Blood from 104 animal patients from urban and rural areas were analyzed finding 53.84% (n=56) having parameters compatibl...

Background and Aims: Ehrlichiosis is an emerging tick-borne zoonotic disease caused by the gramnegative coccid obligate intracellular bacteria of the family Anaplasmataceae. Since the only available evidence in regard to monocytic Ehrlichiosis in Iran is related to dogs, the present study was designed to use the polymerase chain reaction assay for confirming the presence of Ehrlichia spp. in...

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Background The detection of parasites in blood samples by DNA based assays is mostly performed by using the PCR technique, but due to the time of the reactions and costs involved, they still cannot be used in large-scale in routine laboratories. Recently, an alternative are assays based on the technique of Loop-mediated Isothermal Amplification (LAMP), which requires a shorter reaction time, hi...

BACKGROUND Recent advances in bioinformatics have made it possible to predict the B cell and T cell epitopes of antigenic proteins. This has led to design of peptide based vaccines that are more specific, safe, and easy to produce. The obligately intracellular gram negative bacteria Ehrlichia cause ehrlichioses in humans and animals. As yet there are no vaccines to protect against Ehrlichia inf...

Background: Vector-borne infectious and zoonotic diseases are an important health problem that directly affects human and animal health negatively. Results through evaluation of coagulation disorders among vector-borne diseases should be of beneficial for both human and dogs studies. According to the present author’s knowledge reports regarding changes in platelet (PLT) count, prothrombin time ...