Essential hypertension is associated with enhanced biological activity of endothelin-1 (ET-1) and impaired endothelium-dependent vasodilatation. Dihydropyridine calcium antagonists have antioxidant activity in vitro, and they improve endothelial function in vivo. We tested whether calcium antagonists also influence the biological activity of ET-1 in essential hypertensive (EH) patients in the p...

AIM To discover single nucleotide polymorphisms (SNPs) in the promoter region of angiotensin II type 1 receptor (AT1) gene and evaluate their associations with the occurrence of essential hypertension (EH) and coronary heart disease (CHD) in Chinese Han population. METHODS SNPs detection was performed by PCR-sequencing. The genotype was determined by the same method in a total number of 473 u...

BACKGROUND Peroxisome proliferator-activated receptor gamma (PPARG) plays an important role in the pathogenesis and maintenance of essential hypertension (EH). It has been suggested that polymorphisms of PPARG are associated with the risk of EH. However, findings to date remain controversial. To elucidate the associations between the PPARG Pro12Ala and C161T polymorphisms and EH risk, a meta-an...

Cerebrospinal fluid (CSF) and plasma dopamine-beta-hydroxylase (DBH) activity was measured in 22 normotensive (NT), 31 essential hypertensive (EH), and 11 renal hypertensive (RH) patients. Although no differences were observed in their plasma DBH, the mean CSF-DBH activity and specific activity of EH were significantly lower than those of NT and RH patients. Very low CSF-DBH (less than 0.15 uni...

To properly characterize several isolates of Paecilomyces fumosoroseus, a fungal entomopathogen of whiteflies (Homoptera: Aleyrodidae) and other insect pests for biocontrol purposes, virulence towards Trialeurodes vaporariorum, and subtilisin-like (Pr1) and trypsin-like (Pr2) protease activity during propagule production were investigated in monospore cultures (MCs). The virulence of three MCs ...

From the perspective of time domain and frequency domain, we investigate energy harvesting cognitive radio networks (EH-CRNs) with multichannel, where secondary transmitter (ST) opportunistically accesses licensed subchannels to transmit packets by consuming harvested energy. To explore spectrum holes improve lifetime EH-CRNs, ST scavenges from radio-frequency (RF) signal in wide band during (E...

the pathophysiology of primary benign exertional headache (eh) is not still clearly defined. some researchers have suggested an impaired vascular response as the etiology of this disorder. in this study we investigated whether there are any differences in blood pressure (bp) and heart rate (hr) of the subjects in course of the static and dynamic exercises and the treadmill stress test between t...