Background The results of multiple IL-2 clinical trials (using a range of doses) have shown similar trends, in which IL-2 immunotherapy leads to an objective response in 15-20% of patients and complete response in 5-10%. Importantly, the majority (> 80%) of patients with a complete response maintain long-term responses. However, why only a small proportion of patients attain a complete response...

We formulate a stochastic gauge fixing method to study the gauge dependence of Abelian projection. In this method, one can change the gauge from the maximally Abelian one to no gauge fixing continuously. We have found that the linear part of the heavy quark potential from Abelian contribution depends little on the gauge parameter. Similar results have been obtained for the monopole contribution...

“The verifications of Hahnemann convince those who have intellectual integrity for scientific conviction, who will not sacrifice their intellectual integrity to the idols of the day, who will repeat Hahnemann’s experimental verifications of his scientific observations and inductions as they should be repeated. Any other method than to take into the healthy body four drams of China twice a day t...

The shocks and impacts encountered on small high-speed craft exceed the limits set for safe working practice according to current standards. European legislation regarding the exposure to vibration will have far reaching effects on the operators of such craft with respect to the safety of their employees. This paper sets out to highlight the vibration dose values that can be expected during typ...

Background: The present study aimed to investigate the equivalent dose in vital organs, including heart and lung, due to secondary particles produced during breast proton therapy. Materials and Methods: The numerical ORNL female-phantom was improved and simulated using the Monte Carlo MCNPX code. The depth-dose profile of proton beams with different energies was simulated. The proper energy ran...

Background and Aim: Due to the increasing number of radiographic tests, TLD dosimeters can be used to measure the effective dose of critical organs in various radiographic tests. In this research, the progression of analogue to digital radiology devices, which facilitates and accelerates the performance of radiographs, especially emergency patients, was investigated, and then the effective dose...

LY146032, an acidic lipopeptide antibiotic which inhibits the biosynthesis of cell wall peptidoglycan, was found to be effective in delaying death in a hamster model of pseudomembranous colitis. A dose of 0.05 mg/day was effective. The equivalent protection with vancomycin required a dose 100-fold higher, i.e., 5 mg/day.

The paper presents the results of mapping stray radiation fields in three different radiotherapy treatment rooms equipped with three different Co-60 machines. Based on the distribution of the ambient dose equivalent rate, the effective dose to the personnel under various scenarios has been assessed with regard to their movement and position in the room during the preparation of the machine and ...

Background: The annual effective dose equivalent (AEDE) due to ionizing radiation in a coaster area in Nigerian has been determined using Geiger-Muller counter. Materials and Methods: isolevels in the study area were represented by using the kriging interpolation technique on ArcGIS 10.1 software. Duncan multiple range test was performed using Statistical Package for Social Sciences (SPSS). Res...

Neutrinos are present in the natural environment and are also produced by particle accelerators. A recent hypothesis has also been proposed that asserts that ionizing radiation due to neutrinos from certain astronomical events may have led to the extinction of some biological species. Thus, it is of interest to be able to estimate the dose equivalent due to these weakly interacting particles. P...