Carlos M. Duarte* 1 Department of Global Change Research, (Consejo Superior de Investigaciones Científicas-University of the Balearic Islands) Instituto Mediterráneo de Estudios Avanzados, Mallorca, Spain 2 The UWA Oceans Institute, The University of Western Australia, Crawley, WA, Australia 3 Faculty of Biosciences, Fisheries and Economics, University of Tromsø, Tromsø, Norway *Correspondence:...

Where there is conformity across the findings, interpretation and implications of 'clinical' and 'economic' research, there is limited cause for concern. However, there is often unease when apparent contradictory conclusions are drawn from the same study. Given the ever increasing role for economic evaluation in healthcare decision making, this commentary challenges the necessity of compatibili...

BACKGROUND The growth of "big data" and the emphasis on patient-centered health care have led to the increasing use of two key technologies: personalized medicine and digital medicine. For these technologies to move into mainstream health care and be reimbursed by insurers, it will be essential to have evidence that their benefits provide reasonable value relative to their costs. These technolo...

It is now time to begin the study of personal genome services based on the interdisciplinary theories and technologies of genomics and artificial intelligence (AI). Although recently much attention has been given to personal genome services for realizing personal medicine, little systematic research has been done on their communication and computational aspects for intelligent wellness service ...

RoboCup was started in 1997 by a group of Artificial Intelligence and Robotics researchers with the following grand challenge, to be achieved by 2050 [9]: “to build a team of robot soccer players, which can beat a human World Cup champion team.” Since then, RoboCup Federation1 established itself as a structured organization and as one of the major events in the research field of Artificial Inte...

Servitization is a grand challenge for all manufacturing companies to extend their business. As main result this paper presents an approach and corresponding research questions on how to integrate servitization in manufacturing businesses by making use of an innovation ecosystem. Companies might benefit from this approach, as it indicates how relevant characteristics to evolve in order to take ...

In March 2010, the Dagstuhl Seminar 10102 explored the grand challenges confronting research and practice in the domain of discrete event logistics systems. This Executive Summary describes the process of the seminar and discusses the key conclusions regarding grand challenges for research and practice. Abstracts of the presentations given during the seminar are put together in the online proce...