Ebola virus disease (EVD--formerly known as Ebola hemorrhagic fever) is a severe hemorrhagic fever caused by lipid-enveloped, nonsegmented, negative-stranded RNA viruses belonging to the genus Ebolavirus. Case fatality rates may reach up to 76% of infected individuals, making this infection a deadly health problem in the sub-Saharan population. At the moment, there are still no indications on o...

In 2005, a Marburg haemorrhagic fever (MHF) outbreak occurred in Uíge province, Angola, which had its epicentre in Uíge municipality. Concurrently, a health facility located a considerable distance from the outbreak's epicentre reported a drastic reduction in attendance, possibly due to a remote effect of the ongoing MHF outbreak. Health officials should devise strategies to ensure that communi...

10.1128/JCM.40.7.2323-2330.2002. 2002, 40(7):2323. DOI: J. Clin. Microbiol. Günther Asper, Marcus Panning, Herbert Schmitz and Stephan Christian Drosten, Stephan Göttig, Stefan Schilling, Marcel Transcription-PCR Yellow Fever Virus by Real-Time Reverse Rift Valley Fever Virus, Dengue Virus, and Crimean-Congo Hemorrhagic Fever Virus, of Ebola and Marburg Viruses, Lassa Virus, Rapid Detection and...

Since the Ebola outbreak began in March, 2014, 25 178 cases of Ebola have been reported. To control spread of Ebola in west African communities, vaccination campaigns have been proposed. However, the efficacy of candidate Ebola vaccines for primary prevention has not been proven. Furthermore, in communities in which Ebola transmission might be ongoing, an important question is: how will such a ...

In late 2013, the largest documented outbreak of Ebola hemorrhagic fever started in Guinea and has since spread to neighboring countries, resulting in almost 27,000 cases and >11,000 deaths in humans. In March 2014, Ebola virus (EBOV) was identified as the causative agent. This study compares the pathogenesis of a new EBOV strain, Makona, which was isolated in Guinea in 2014 with the prototype ...

OBJECTIVES To describe haemorrhagic pleural effusion as a rare complication of brucellosis that finally needed lung decortication. CLINICAL PRESENTATION AND INTERVENTION A 37-year-old female presented with a 1-week history of fever, dry cough and pleuritic chest pain. Physical examination showed signs of right pleural effusion and hepatosplenomegaly. Complete blood count showed pancytopenia, ...

Recent events in West Africa have highlighted the potential for the viral haemorrhagic fevers (VHFs) to cause considerable mortality and morbidity among heathcare workers. However, this is not a new threat as, although the risk is currently increased, it has always been present. In South Africa (SA) the only endemic haemorrhagic fever is Crimean-Congo haemorrhagic fever, transmitted by the Hyal...

Fifteen (14%) of 105 women with Ebola hemorrhagic fever hospitalized in the isolation unit of the Kikwit General Hospital (Democratic Republic of the Congo) were pregnant. In 10 women (66%) the pregnancy ended with an abortion. In 3 of them, a curettage was performed, and all 3 received a blood transfusion from an apparently healthy person. One woman was prematurely delivered of a stillbirth. F...

HISTORY ABSTRACT: Ebola Hemorrhagic Fever (EHF) is a deadly infection which has no cure till today. Treating the symptoms and supportive care are the main stay in the management of the disease. There are some treatments and vaccines in initial stage of development but, they are never tested on humans. BACKGROUND:According to New York Times recent outbreak of Ebola Hemorrhagic fever (EHF) or Ebo...