AIM ; To study the effect of reproductive factors on breast cancer risk in Niger Delta women. SETTING: University of Benin Teaching Hospital and Central Hospital Benin. DESIGN: Case-control study. SUBJECTS: Seventy one women diagnosed with breast cancer and their age-matched controls. FINDINGS: Mean age of cases was 46.7 years, control was 45.7 years. Family history of breast cancer RR2.03 P 0....

Adopted children show more problem behaviors than nonadopted children. Given that internationally-adopted individuals show earlier puberty than non-adopted individuals, and early puberty is associated with problem behaviors in nonadopted youth, we analyzed data from domestic adoptees to determine whether problem behaviors could be explained by differences in pubertal timing. Relative to nonadop...

the present study was initiated to derive an indirect method for estimating body fat mass (bfm) and to evaluate the correlation between indirect anthropometric techniques for this estimation and to examine the relation of these parameters and of iq to age of menarche. a total of 578 adolescent girls of ten junior high schools in five educational districts of mashhad, participated in a cross sec...

BACKGROUND Declining age at menarche has been observed in many countries. In China, a decrease of 4.5 months per decade in the average age at menarche among the majority Han girls has recently been reported. However, the trends in age at menarche among ethnic minority girls over the past 25 years remain unknown. OBJECTIVES To compare the differences in median age at menarche among girls aged ...

Early and late puberty pose a risk for many problems later in life. Various theories suggest that child sexual abuse victimization may either accelerate or delay the onset of puberty. This systematic literature review examines relationship between age girls. Fourteen scientific studies were included analyzed. There is an association early at menarche girls, but there insufficient evidence with ...

BACKGROUND Improvements in socioeconomic conditions and population health have been linked to declining age at menarche. In China, secular trends in age at menarche following extensive economic reform during recent decades have not been thoroughly investigated. This study examined the overall trend in age at menarche and assessed differences in the rate of change of age at menarche over time, a...

The primary cause for this high mortality rate is the failure to detect ovarian cancer at an initial stage. Difficulties in early detection are associated with the absence of effective population screening methods and specific signs and symptoms characteristic for initial stages of disease [23-27]. The risk of developing ovarian cancer increases with age; other risk factors include inflammation...

A woman's age at menarche (first menstrual period) and her age at menopause are the alpha and omega of her reproductive years. The timing of these milestones is critical for a woman's health trajectory over her lifespan, as they are indicators of ovarian function and aging. Both early and late timing of either event are associated with risk for adverse health and psychosocial outcomes. Thus, th...

Endogenous estrogens influence mammary gland development during puberty and breast cancer risk during adulthood. Early-life exposure to dietary or environmental estrogens may alter estrogen-mediated processes. Soy foods contain phytoestrogenic isoflavones (IF), which have mixed estrogen agonist/antagonist properties. Here, we evaluated mammary gland responses over time in pubertal female cynomo...

BACKGROUND Menarche delay has been reported in adolescent females with type 1 diabetes (T1DM), perhaps due to poor glycemic control. We sought to compare age at menarche between adolescent females with T1DM and national data, and to identify factors associated with delayed menarche and menstrual irregularity in T1DM. METHODS This was a cross-sectional study and females ages 12- 24 years (n = ...