We construct an endogenous growth model of directed technical change with automation (the introduction of machines which replace low-skill labor and complement high-skill labor) and horizontal innovation (the introduction of new products, which increases demand for both types of labor). For general processes of technical change, we demonstrate that although low-skill wages can drop during perio...

The Aggregate Effects of Trade and Migration: Evidence from OECD Countries Two large but separate bodies of literature analyze the economic effects of international trade and immigration. Given that several factors are important determinants of both trade and migration flows, the previous studies are vulnerable to a potentially serious omitted-variables bias, questioning the validity of existin...

We show modern information technology (in short IT) is the cause of rising income and wealth inequality since the 1970's and has contributed to slow growth of wages and decline in the natural rate. We first study all US firms whose securities trade on public exchanges. Surplus wealth of a firm is the difference between wealth created (equity and debt) and its capital. We show (i) aggregate surp...

Abstract Objective. Research examining psychological and physiological benefits of Qigong and Tai Chi is growing rapidly. The many practices described as Qigong or Tai Chi have similar theoretical roots, proposed mechanisms of action, and expected benefits. Research trials and reviews, however, treat them as separate targets of examination. This review examines the evidence for achieving outcom...

1 Fanburg-Smith JC, Michal M, Partanen TA, Alitalo K, Miettinen M. Papillary intralymphatic angioendothelioma (PILA): a report of twelve cases of a distinctive vascular tumor with phenotypic features of lymphatic vessels. Am J Surg Pathol 1999; 23: 1004–1010. 2 McKee PH, Calonje E, Grantner SR, eds. Pathology of the Skin, 3rd edn. Elsevier Mosby, London, 2005: 1829–1830 3 Weedon D. Weedon’s Ski...

During lytic herpes simplex virus (HSV) infections, the HSV virion host shutoff protein (UL41) accelerates the turnover of host and viral mRNAs. Although the UL41 polypeptides from HSV type 1 (HSV-1) strain KOS and HSV-2 strain 333 are 87% identical, HSV-2 strains generally shut off the host more rapidly and completely than HSV-1 strains. In a previous study, we identified three regions of the ...

The baculovirus expression vector system (BEVS) has become an important platform for the of recombinant proteins and is especially useful production large protein complexes such as virus-like particles (VLPs). An application VLPs their use vehicles targeted delivery drugs or toxins which requires development methods efficient loading with intended cargo. Our research intends to employ BEVS inse...

A pandemia da COVID-19, provocou um grande impacto na saúde mental das pessoas, mesmo após a fase aguda doença, resultando em altas taxas de ansiedade e depressão, tornando necessário o desenvolvimento avaliação tratamentos, não farmacológicos, eficazes para aliviar esses sintomas. Este estudo quase-experimental, aberto, unicêntrico, realizado nos meses fevereiro março 2023, no ambulatório enfe...

Lactobacillus delbrueckii UFV-H2b20 has been shown to increase clearance of bacteria injected into the blood of germ-free mice. Moreover, it induces the production of type 1 cytokines by human peripheral mononuclear cells. The objective of the present study was to investigate the production of inflammatory cytokines [interleukin-12 (IL-12 p40), tumor necrosis factor-alpha (TNF-alpha), and inter...