BACKGROUND AND OBJECTIVES The prognosis and natural history of bradycardia related to drugs such as beta-blockers and non-dihydropyridine calcium channel blockers are not well known. SUBJECTS AND METHODS We retrospectively analyzed 38 consecutive patients (age 69+/-11, 21 women) with drug-related bradycardia (DRB) between March 2005 and September 2007. A drug-associated etiology for the brady...

I show that US prescription drug prices can be better understood by accounting for history-dependent demand and industry pricing structure, which has important implications for potential government negotiation. First, I confirm the presence of inertia and history-dependent demand for generic drugs through a novel quasiexperiment. Next, I capture pricing structure in a dynamic pricing game invol...

AIM Drug-induced autoimmune hepatitis (DIAIH) remains poorly characterized. Our aim was to assess natural history and outcomes in DIAIH. METHODS This was a retrospective cohort study. RESULTS Eighty-two patients with autoimmune hepatitis (AIH) were identified, 11 (13.4%) with DIAIH, implicated drugs being nitrofurantoin (n = 4), statins (n = 4), herbal remedies (n = 2) and diclofenac (n = 1...

background and objectives: intravenous drug using is a main risk factor for getting infected with hiv, hepatitis b and c viruses. the syphilis is a common infection. the aim of this study was to investigate the seroepidemiology of hiv, syphilis, hepatitis b and c among the intravenous drug users (idus) at loghman hakim hospital, tehran. materials & methods: a descriptive (cross- sectional) stud...

Background: Various studies have tested quality of life (QOL) among drug addicts, however very few have reported any association between oral health-related quality of life (OHRQOL) and mode of drug administration among drug addicts. Hence, the present study was conducted aiming to evaluate the impact of mode of administration of drugs on OHRQOL among drug addicts. Methods: Data was collected u...

BACKGROUND Trypanosomosis caused by Trypanosoma congolense is a major constraint to animal health in sub-Saharan Africa. Unfortunately, the treatment of the disease is impaired by the spread of drug resistance. Resistance to diminazene aceturate (DA) in T. congolense is linked to a mutation modifying the functioning of a P2-type purine-transporter responsible for the uptake of the drug. Our obj...

OBJECTIVE To determine the incidence of drug related problems that fail to be noted on casualty cards in patients subsequently admitted, and to compare medication histories as recorded by accident and emergency (A&E) senior house officers (SHOs) and a pharmacist. METHODS An initial retrospective survey of 1459 acute inpatient admissions through A&E over a three month period was followed by a ...

Background: Drug abuse is a major health problem in many countries. Noticing the different patterns of drug abuse in different areas, we evaluated the epidemiology of drug abuse and related factors in Fars province, Southern Iran. Materials and Methods: In a one-year cross-sectional study, from March 21st, 2009 to 2010, all subjects referring to Addiction Treatment Clinic of Shiraz University ...

This study investigates the association between drug use and lifetime suicidal behaviors among Asian American women (n = 720) residing throughout Massachusetts, using data collected from 2010 to 2011. Logistic regression models identified that a history of hard drug use alone or in combination with soft drug use has a significant association with both suicidal ideation and suicide attempts amon...

Methods Patients with a history of drug allergies which were addressed to consultations by general practitioners were consulted in the Pulmonology and Allergology department in the period 2010-2013. The questionnaires and DPTs with the culprit drug or alternative medications were performed according to ENDA rules. Patients were divided into two groups depending on their clinical history and rea...